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Migraine: Telcagepant provides new hope for people with migraine.

作者信息

Edvinsson Lars

出版信息

Nat Rev Neurol. 2009 May;5(5):240-2. doi: 10.1038/nrneurol.2009.49.

DOI:10.1038/nrneurol.2009.49
PMID:19488079
Abstract
摘要

相似文献

1
Migraine: Telcagepant provides new hope for people with migraine.偏头痛：替卡格雷为偏头痛患者带来了新希望。
Nat Rev Neurol. 2009 May;5(5):240-2. doi: 10.1038/nrneurol.2009.49.
2
CGRP antagonists: hope for a new era in acute migraine treatment.降钙素基因相关肽拮抗剂：急性偏头痛治疗新时代的希望。
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3
ACS chemical neuroscience molecule spotlight on Telcagepant (MK-0974).ACS 化学神经科学分子特写：Telcagepant（MK-0974）。
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Clinical and preclinical rationale for CGRP-receptor antagonists in the treatment of migraine.降钙素基因相关肽（CGRP）受体拮抗剂治疗偏头痛的临床及临床前理论依据
Headache. 2008 Sep;48(8):1259-68. doi: 10.1111/j.1526-4610.2008.01214.x.
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Calcitonin gene-related peptide (CGRP) receptor antagonists in the treatment of migraine.降钙素基因相关肽（CGRP）受体拮抗剂在偏头痛治疗中的应用。
CNS Drugs. 2010 Jul;24(7):539-48. doi: 10.2165/11534920-000000000-00000.
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Efficacy, safety, and tolerability of telcagepant in the treatment of acute migraine: a meta-analysis.替卡格雷治疗急性偏头痛的疗效、安全性及耐受性：一项荟萃分析。
Pain Pract. 2015 Feb;15(2):124-31. doi: 10.1111/papr.12158. Epub 2013 Dec 30.
7
Telcagepant, a calcitonin gene-related peptide antagonist for the treatment of migraine.替卡格雷泮，一种用于治疗偏头痛的降钙素基因相关肽拮抗剂。
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Optimal balance of efficacy and tolerability of oral triptans and telcagepant: a review and a clinical comment.口服曲坦类药物和替利加喷与耐受性的最佳平衡：综述和临床评论。
J Headache Pain. 2011 Jun;12(3):275-80. doi: 10.1007/s10194-011-0309-5. Epub 2011 Feb 25.
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Randomized, controlled trial of telcagepant for the acute treatment of migraine.替卡格雷用于偏头痛急性治疗的随机对照试验
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本文引用的文献

1
Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial.降钙素基因相关肽受体新型口服拮抗剂MK-0974（替卡普坦）与佐米曲普坦治疗急性偏头痛的疗效及耐受性比较：一项随机、安慰剂对照、平行治疗试验
Lancet. 2008 Dec 20;372(9656):2115-23. doi: 10.1016/S0140-6736(08)61626-8. Epub 2008 Nov 25.
2
Calcitonin gene-related peptide receptor antagonism does not affect the severity of myocardial ischemia during atrial pacing in dogs with coronary artery stenosis.在冠状动脉狭窄的犬心房起搏期间，降钙素基因相关肽受体拮抗作用不影响心肌缺血的严重程度。
J Pharmacol Exp Ther. 2009 Feb;328(2):571-8. doi: 10.1124/jpet.108.144220. Epub 2008 Nov 7.
3
Central projections of the sensory innervation of the rat middle meningeal artery.大鼠脑膜中动脉感觉神经支配的中枢投射
Brain Res. 2008 May 7;1208:103-10. doi: 10.1016/j.brainres.2008.02.078. Epub 2008 Mar 7.
4
Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine.口服降钙素基因相关肽（CGRP）受体拮抗剂MK-0974用于偏头痛急性治疗的随机对照试验
Neurology. 2008 Apr 15;70(16):1304-12. doi: 10.1212/01.WNL.0000286940.29755.61. Epub 2007 Oct 3.
5
Triptan-induced contractile (5-HT1B receptor) responses in human cerebral and coronary arteries: relationship to clinical effect.曲坦类药物诱发的人脑血管和冠状动脉收缩（5-HT1B受体）反应：与临床疗效的关系。
Clin Sci (Lond). 2005 Sep;109(3):335-42. doi: 10.1042/CS20050016.
6
Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine.降钙素基因相关肽受体拮抗剂BIBN 4096 BS用于偏头痛的急性治疗。
N Engl J Med. 2004 Mar 11;350(11):1104-10. doi: 10.1056/NEJMoa030505.
7
Effect of the CGRP receptor antagonist BIBN4096BS in human cerebral, coronary and omental arteries and in SK-N-MC cells.降钙素基因相关肽（CGRP）受体拮抗剂BIBN4096BS对人脑动脉、冠状动脉、网膜动脉及SK-N-MC细胞的作用。
Eur J Pharmacol. 2002 Jan 2;434(1-2):49-53. doi: 10.1016/s0014-2999(01)01532-1.
8
Oral triptans (serotonin 5-HT(1B/1D) agonists) in acute migraine treatment: a meta-analysis of 53 trials.急性偏头痛治疗中口服曲坦类药物（5-羟色胺5-HT(1B/1D)激动剂）：53项试验的荟萃分析
Lancet. 2001 Nov 17;358(9294):1668-75. doi: 10.1016/S0140-6736(01)06711-3.
9
Calcitonin gene-related peptide: functional role in cerebrovascular regulation.降钙素基因相关肽：在脑血管调节中的功能作用。
Proc Natl Acad Sci U S A. 1986 Aug;83(15):5731-5. doi: 10.1073/pnas.83.15.5731.
10
Vasoactive peptide release in the extracerebral circulation of humans during migraine headache.偏头痛发作时人体脑外循环中血管活性肽的释放
Ann Neurol. 1990 Aug;28(2):183-7. doi: 10.1002/ana.410280213.