Pircher Michael, Götzinger Erich, Leitgeb Rainer, Sattmann Harald, Findl Oliver, Hitzenberger Christoph
Opt Express. 2004 Nov 29;12(24):5940-51. doi: 10.1364/opex.12.005940.
Recently, we developed a phase resolved polarization sensitive OCT system based on transversal scanning. This system was now improved and adapted for retinal imaging in vivo. We accelerated the image acquisition speed by a factor of 10 and adapted the system for light sources emitting at 820nm. The improved instrument records 1000 transversal lines per second. Two different scanning modes enable either the acquisition of high resolution B-scan images containing 1600x500 pixels in 500ms or the recording of 3D data sets by C-scan mode imaging. This allows acquiring a 3D-data set containing 1000x100x100 pixels in 10 seconds. We present polarization sensitive B-scan images and to the best of our knowledge, the first 3D-data sets of retardation and fast axis orientation of fovea and optic nerve head region in vivo. The polarizing and birefringence properties of different retinal layers: retinal pigment epithelium, Henle's fiber layer, and retinal nerve fiber layer are studied.
最近，我们开发了一种基于横向扫描的相位分辨偏振敏感光学相干断层扫描（OCT）系统。该系统现已改进并适用于活体视网膜成像。我们将图像采集速度提高了10倍，并使该系统适用于发射波长为820nm的光源。改进后的仪器每秒记录1000条横向线。两种不同的扫描模式，既可以在500毫秒内采集包含1600x500像素的高分辨率B扫描图像，也可以通过C扫描模式成像记录三维数据集。这使得在10秒内能够采集包含1000x100x100像素的三维数据集。我们展示了偏振敏感B扫描图像，据我们所知，这是首次获得的活体中央凹和视神经乳头区域的延迟和快轴方向的三维数据集。研究了不同视网膜层（视网膜色素上皮、亨利纤维层和视网膜神经纤维层）的偏振和双折射特性。
