Duarte Leonardo Teixeira Domingues, Paes Franklin Cespedes, Fernandes Maria do Carmo Barreto C, Saraiva Renato Angelo
Departamento de Anestesiologia Rede SARAH de Hospitais de Reabilitação SMHS 501, Conjunto A, Asa Sul70330-150 Brasília DF.
Rev Bras Anestesiol. 2009 May-Jun;59(3):273-85. doi: 10.1590/s0034-70942009000300002.
Posterior lumbar plexus block promotes effective postoperative analgesia in total knee arthroplasty. Ropivacaine and bupivacaine do not show differences in analgesic efficacy when used in different peripheral nerve blocks. The objective of this study was to compare the efficacy of postoperative analgesia resulting from the administration of a single dose of 0.5% bupivacaine or 0.5% ropivacaine in posterior lumbar plexus block for total hip arthroplasty.
Thirty-seven patients were randomly divided in two groups according to the local anesthetic used: Group B - 0.5% bupivacaine with 1:200,000 epinephrine; or group R - 0.5% ropivacaine. During the postoperative period, pain scores and morphine consumption in patient controlled analgesia were compared between groups. Bleeding during surgery and the incidence of side effects and complications were also compared.
Although pain scores were lower in Group R 8 hours, 12 hours, and 24 hours after the blockade, these differences were not clinically significant. Multiple linear regression identified the local anesthetic as an independent variable. Differences in morphine consumption, intraoperative bleeding, and the incidence of complications and side effects were not observed between both groups.
0.5% Bupivacaine and 0.5% ropivacaine produced effective and prolonged postoperative pain relief after total hip arthroplasty, without clinical differences, when equivalent doses were administered for posterior lumbar plexus block.
腰丛后路阻滞可促进全膝关节置换术后的有效镇痛。罗哌卡因和布比卡因用于不同的周围神经阻滞时,镇痛效果无差异。本研究的目的是比较在全髋关节置换术的腰丛后路阻滞中,单次给予0.5%布比卡因或0.5%罗哌卡因后的术后镇痛效果。
37例患者根据所用局部麻醉药随机分为两组:B组——0.5%布比卡因加1:200,000肾上腺素;R组——0.5%罗哌卡因。术后比较两组患者的疼痛评分及患者自控镇痛中的吗啡用量。同时比较手术中的出血量以及副作用和并发症的发生率。
尽管在阻滞后8小时、12小时和24小时R组的疼痛评分较低,但这些差异无临床意义。多元线性回归将局部麻醉药确定为一个自变量。两组之间在吗啡用量、术中出血以及并发症和副作用的发生率方面未观察到差异。
在腰丛后路阻滞给予等效剂量时,0.5%布比卡因和0.5%罗哌卡因在全髋关节置换术后均产生了有效且持久的术后疼痛缓解,无临床差异。