上下气道重塑。
Remodeling of the lower and upper airways.
机构信息
HC, FM, USP.
出版信息
Braz J Otorhinolaryngol. 2009 Jan-Feb;75(1):151-6. doi: 10.1016/s1808-8694(15)30847-8.
UNLABELLED
Remodeling is defined as modeling again or differently, as reconstructing. Remodeling is a critical aspect of wound repair in all organs; it represents a dynamic process that associates the production and degradation of matrix in reaction to inflammation. This leads to normal reconstruction or a pathologic process.
AIM AND METHODS
To compare data in the current literature on upper and lower airways.
RESULTS
Asthma is a chronic inflammatory disease associated with abnormal airways remodeling. In allergic rhinitis, another chronic inflammatory disease, remodeling is still poorly understood. Even though inflammation is similar in allergic rhinitis and asthma, the pathologic extent of nasal remodeling, as well as its clinical consequences, might be different from those in bronchi.
CONCLUSION
Remodeling occurs less in upper airways compared to lower airways; it is apparent, however, that the structure of the rhinitic nose is not normal.
未加标签
重塑的定义是再次或不同地建模，即重建。重塑是所有器官伤口修复的关键方面；它是一个动态过程，与炎症反应中基质的产生和降解有关。这导致正常重建或病理性过程。
目的和方法
比较当前文献中上、下呼吸道的数据。
结果
哮喘是一种与气道异常重塑相关的慢性炎症性疾病。在另一种慢性炎症性疾病变应性鼻炎中，重塑仍知之甚少。尽管变应性鼻炎和哮喘的炎症相似，但鼻重塑的病理性程度及其临床后果可能与支气管不同。
结论
与下呼吸道相比，上呼吸道的重塑程度较低；然而，很明显，鼻炎的鼻子结构不正常。
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