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磨牙症影响应激大鼠的应激反应。

Bruxism affects stress responses in stressed rats.

机构信息

Department of Craniofacial Growth and Development Dentistry, Research Institute of Occlusion Medicine, Research Center of Brain and Oral Science, Kanagawa Dental College, Yokosuka, Kanagawa, Japan.

出版信息

Clin Oral Investig. 2010 Apr;14(2):153-60. doi: 10.1007/s00784-009-0280-6. Epub 2009 Jun 2.

DOI:10.1007/s00784-009-0280-6
PMID:19488797
Abstract

It has been proposed that suppression of stress-related emotional responses leads to the simultaneous activation of both sympathetic and parasympathetic divisions of the autonomic nervous system (ANS) and that the expression of these emotional states has a protective effect against ulcerogenesis. In the present study, we investigated whether stress-induced bruxism activity (SBA) has a physiological effect of on the stress-induced changes of the stomach, thymus, and spleen as well as blood leukocytes, cortisol, and adrenaline. This study demonstrated that SBA attenuated the stress-induced ulcer genesis as well as degenerative changes of thymus and spleen. SBA also attenuated increases of adrenaline, cortisol, and neutrophils in the blood. In conclusion, expression of aggression through SBA during stress exposure attenuates both stress-induced ANS response, including gastric ulcer formation.

摘要

有人提出,抑制与压力相关的情绪反应会导致自主神经系统(ANS)的交感和副交感两部分同时激活,而这些情绪状态的表达对溃疡形成有保护作用。在本研究中,我们研究了压力诱导的磨牙症活动(SBA)是否对压力引起的胃、胸腺和脾脏以及血液白细胞、皮质醇和肾上腺素的变化有生理影响。本研究表明,SBA 可减轻压力引起的溃疡形成以及胸腺和脾脏的退行性变化。SBA 还可减轻血液中肾上腺素、皮质醇和中性粒细胞的增加。总之,在压力暴露期间通过 SBA 表达的攻击性会减弱包括胃溃疡形成在内的压力诱导的 ANS 反应。

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