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极早产儿童在学龄早期的执行功能

Executive function in very preterm children at early school age.

作者信息

Aarnoudse-Moens Cornelieke S H, Smidts Diana P, Oosterlaan Jaap, Duivenvoorden Hugo J, Weisglas-Kuperus Nynke

机构信息

Department of Pediatrics, Division of Neonatology, Erasmus University Medical Centre Sophia Children's Hospital Rotterdam, Rotterdam, The Netherlands.

出版信息

J Abnorm Child Psychol. 2009 Oct;37(7):981-93. doi: 10.1007/s10802-009-9327-z.

Abstract

We examined whether very preterm (< or =30 weeks gestation) children at early school age have impairments in executive function (EF) independent of IQ and processing speed, and whether demographic and neonatal risk factors were associated with EF impairments. A consecutive sample of 50 children (27 boys and 23 girls) born very preterm (mean age = 5.9 years, SD = 0.4, mean gestational age = 28.0 weeks, SD = 1.4) was compared to a sample of 50 age-matched full-term controls (23 girls and 27 boys, mean age = 6.0 years, SD = 0.6) with respect to performance on a comprehensive EF battery, assessing the domains of inhibition, working memory, switching, verbal fluency, and concept generation. The very preterm group demonstrated poor performance compared to the controls on all EF domains, even after partialing out the effects of IQ. Processing speed was marginally related to EF. Analyses with demographic and neonatal risk factors showed maternal education and gestational age to be related to EF. This study adds to the emerging body of literature showing that very preterm birth is associated with EF impairments.

摘要

我们研究了极早产(孕周≤30周)的儿童在学龄早期是否存在独立于智商和处理速度的执行功能(EF)损伤,以及人口统计学和新生儿风险因素是否与EF损伤相关。将50名极早产儿童(27名男孩和23名女孩,平均年龄=5.9岁,标准差=0.4,平均孕周=28.0周,标准差=1.4)的连续样本与50名年龄匹配的足月对照儿童(23名女孩和27名男孩,平均年龄=6.0岁,标准差=0.6)在一套综合EF测试中的表现进行比较,该测试评估抑制、工作记忆、转换、语言流畅性和概念生成等领域。即使在排除智商的影响后,极早产组在所有EF领域的表现仍比对照组差。处理速度与EF有微弱关联。对人口统计学和新生儿风险因素的分析表明,母亲教育程度和孕周与EF有关。这项研究为新出现的文献增添了内容,表明极早产与EF损伤有关。

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