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[分娩潜伏期硬膜外镇痛:对产程及分娩方式的影响]

[Epidural analgesia in latent phase of labor: effects on length of labor and mode of delivery].

作者信息

Geng Zhi-Yu, Wu Xin-Min, Li Ping, Fu Ying-Ying

机构信息

Department of Anesthesiology, First Hospital, Peking University, Beijing 100034, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2009 Jan 6;89(1):33-6.

Abstract

OBJECTIVE

To compare the outcome of ropivacaine plus sufentanil for patient-controlled epidural analgesia between nulliparous women presenting in latent and active labor.

METHODS

360 nulliparous parturients were randomized according to cervix dilation. Latent group (cervix dilation < 3 cm) received 0.1% ropivacaine with 0.5 microg/ml sufentanil and active group (cervix dilation > or = 3 cm) receive 0.15% ropivacaine with 0.5 microg/ml sufentanil, both followed by an infusion of 0.1% ropivacaine with 0.5 microg/ml sufentanil through PCEA. The PCEA pump was programmed to infuse a 6 ml bolus with a lockout interval of 15-20 min. The following were recorded: (1) pain intensity evaluated using VAS (0-10), (2) motor block assessed using modified Bromage scale, (3) onset of analgesia after epidural injection, (4) fetal heart rate, (5) maternal vital signs, (6) apgar score, (7) labor process, (8) mode of delivery and (9) the total amount of analgesic consumed.

RESULTS

Both groups provided good analgesia. Early administration of epidural analgesia did not prolong the duration of first and second stage of labor. However, group L had a significant higher caesarean section rate and a significant lower instrumental delivery rate than group A. The reasons of cesarean section in both groups were arrested active phase and fetal distress. The reasons of instrumental delivery in both groups were fetal distress. The neonates had good outcome in both groups.

CONCLUSIONS

Compared with epidural analgesia in active phase of labor, early administration of epidural analgesia in latent phase did not prolong labor, however, the caesarean section rate was increased and instrumental delivery rate was decreased.

摘要

目的

比较罗哌卡因联合舒芬太尼用于初产妇潜伏期和活跃期分娩自控硬膜外镇痛的效果。

方法

360例初产妇根据宫颈扩张程度随机分组。潜伏期组(宫颈扩张<3 cm)接受0.1%罗哌卡因加0.5μg/ml舒芬太尼,活跃期组(宫颈扩张≥3 cm)接受0.15%罗哌卡因加0.5μg/ml舒芬太尼,两组均通过PCEA持续输注0.1%罗哌卡因加0.5μg/ml舒芬太尼。PCEA泵设置为单次注入6 ml,锁定时间间隔为15 - 20分钟。记录以下指标:(1)采用视觉模拟评分法(VAS,0 - 10分)评估疼痛强度;(2)采用改良Bromage量表评估运动阻滞;(3)硬膜外注射后镇痛起效时间;(4)胎儿心率;(5)产妇生命体征;(6)阿氏评分;(7)产程;(8)分娩方式;(9)镇痛药物总消耗量。

结果

两组均提供了良好的镇痛效果。早期实施硬膜外镇痛并未延长第一产程和第二产程的时间。然而,潜伏期组的剖宫产率显著高于活跃期组,器械助产率显著低于活跃期组。两组剖宫产的原因均为活跃期停滞和胎儿窘迫。两组器械助产的原因均为胎儿窘迫。两组新生儿结局良好。

结论

与活跃期分娩时实施硬膜外镇痛相比,潜伏期早期实施硬膜外镇痛并未延长产程,但剖宫产率增加,器械助产率降低。

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