67种膀胱和前列腺各种疾病中尿路上皮结构改变的刻板印象。

67 stereotypes of structural modification of the urothelium in various diseases of the urinary bladder and prostate.

作者信息

Nepomnyashchikh G I, Aidagulova S V, Nepomnyashchikh D L, Boboev M M, Isaenko V I, Abdullaev N A, Ivaninskii O I, Kunin I S

机构信息

Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia.

出版信息

Bull Exp Biol Med. 2008 Oct;146(4):415-9. doi: 10.1007/s10517-009-0308-6.

DOI:10.1007/s10517-009-0308-6

PMID:19489309

Abstract

Structural modification of the urothelium was studied in various diseases of the urinary bladder and prostate, including urinary bladder cancer, vibration cystopathy, chronic prostatitis, benign prostate hyperplasia, and chronic cystitis. The general phenomena of changes in urinary bladder epithelium were atrophy, squamous metaplasia, and instability of the urothelium (focal atrophy, dysplasia, hyperplasia, and metaplasia). This phenomenon can be interpreted as a morphological marker for cancer risk.

摘要

在膀胱和前列腺的各种疾病中研究了尿路上皮的结构改变，包括膀胱癌、振动性膀胱炎、慢性前列腺炎、良性前列腺增生和慢性膀胱炎。膀胱上皮变化的一般现象为萎缩、鳞状化生以及尿路上皮不稳定（局灶性萎缩、发育异常、增生和化生）。这种现象可被解释为癌症风险的形态学标志物。