Suh Dong-Churl, Kim Chul-Min, Choi In-Sun, Plauschinat Craig A, Barone Joseph A
Rutgers University, Piscataway, New Jersey 08854, USA.
J Hypertens. 2009 Sep;27(9):1908-16. doi: 10.1097/HJH.0b013e32832d4aee.
The objectives of this study were to examine the trends in the prevalence of type 2 diabetic patients with comorbid hypertension and blood pressure (BP) control rates in the United States and determine factors associated with these outcomes.
We used data from National Health and Nutrition Examination Surveys (NHANES) III (1988-1994) and NHANES 1999-2004, a cross-sectional sample of the noninstitutionalized US populations. Type 2 diabetic patients were identified as patients at least 30 years of age with physician-diagnosed diabetes who were taking insulin or oral antidiabetic drugs to manage the condition. A diagnosis of hypertension was based on physician diagnosis, treatment with antihypertensive medications, or BP at least 140/90 mmHg. BP control was defined as diabetic patients who maintained BP <130/80 mmHg. Logistic regression was used to estimate risks of high BP, and odds of high BP treatment and control rates, after adjusting for demographic and clinical risk factors.
The age-adjusted prevalence of diabetic patients and those with hypertension increased significantly from 5.8 to 7.1% and 3.9 to 4.7%, respectively, from NHANES III to NHANES 1999-2004. Among diabetic patients with hypertension, patients who were treated with medication or lifestyle or behavioral modification therapy have increased significantly from 76.5 to 87.8% during the observation period. The proportion of patients who controlled BP increased from 15.9 to 29.6%, but 70% of patients still did not meet the target BP goal.
Aggressive public health efforts are needed to improve BP control in type 2 diabetic patients with hypertension.
本研究的目的是调查美国2型糖尿病合并高血压患者的患病率趋势以及血压(BP)控制率,并确定与这些结果相关的因素。
我们使用了来自国家健康和营养检查调查(NHANES)III(1988 - 1994年)和NHANES 1999 - 2004年的数据,这是美国非机构化人群的横断面样本。2型糖尿病患者被确定为年龄至少30岁、经医生诊断患有糖尿病且正在使用胰岛素或口服降糖药物治疗的患者。高血压的诊断基于医生诊断、使用抗高血压药物治疗或血压至少为140/90 mmHg。血压控制定义为血压维持在<130/80 mmHg的糖尿病患者。在调整了人口统计学和临床风险因素后,使用逻辑回归来估计高血压风险以及高血压治疗和控制率的比值比。
从NHANES III到NHANES 1999 - 2004年,年龄调整后的糖尿病患者和高血压患者的患病率分别从5.8%显著增加到7.1%和从3.9%增加到4.7%。在患有高血压的糖尿病患者中,在观察期内接受药物治疗或生活方式或行为改变治疗的患者从从76.5%显著增加到87.8%。血压得到控制的患者比例从15.9%增加到29.6%,但仍有70%的患者未达到目标血压值。
需要积极开展公共卫生工作以改善2型糖尿病合并高血压患者的血压控制情况。