Rana Juwel, Oldroyd John, Islam Md Momin, Tarazona-Meza Carla E, Islam Rakibul M
Department of Public Health, School of Health and Life Sciences, North South University, Dhaka, Bangladesh.
Department of Biostatistics and Epidemiology, University of Massachusetts Amherst, Massachusetts, USA.
Int J Cardiol Hypertens. 2020 Oct 26;7:100061. doi: 10.1016/j.ijchy.2020.100061. eCollection 2020 Dec.
This study aims to compare the prevalence of hypertension (HTN) and controlled hypertension (CHTN) in US adults and determine the absolute difference in the prevalence of HTN and CHTN between the JNC7 and ACC/AHA 2017 guidelines.
Data for this study were derived from the most recent cycle of the National Health and Nutrition Examination Survey (NHANES) 2017-2018. After excluding participants with missing systolic blood pressure (BP) or diastolic BP and aged <18 years, 4730 participants were included in the final analyses. BP was defined as the average of the first three measurements. The prevalence of HTN and CHTN, including absolute differences of these prevalences, were estimated using both JNC7 and ACC/AHA 2017 guidelines.
The overall weighted prevalence of HTN was 31.7% (95% CI: 28.7-34.8) based on JNC7, while the corresponding prevalence was 45.6% (95% CI: 43.0-48.3) when new guideline of ACC/AHA was used. Of the people who had HTN according to the JNC7 and ACC/AHA 2017 guidelines, 48.2% (95% CI: 44.4-52.0) and 21.0% (95% CI: 18.1-24.2) had a controlled blood pressure level, respectively. When blood pressure was assessed using both guidelines, the greatest absolute increase in rates of HTN and CHTN was 17.4% and 30.0% in people aged 40-59 years, respectively.
Given the high burden of disease due to complications arising from untreated HTN, as well as the higher costs of untreated disease, new guidelines have important public health implications to early detection of patients at risk and prevent complications across different populations.
本研究旨在比较美国成年人中高血压(HTN)和血压得到控制的高血压(CHTN)的患病率,并确定JNC7与美国心脏病学会/美国心脏协会(ACC/AHA)2017年指南之间HTN和CHTN患病率的绝对差异。
本研究的数据来自2017 - 2018年国家健康与营养检查调查(NHANES)的最新周期。在排除收缩压(BP)或舒张压数据缺失以及年龄<18岁的参与者后,最终分析纳入了4730名参与者。血压定义为前三次测量的平均值。使用JNC7和ACC/AHA 2017年指南估计HTN和CHTN的患病率,包括这些患病率的绝对差异。
根据JNC7,HTN的总体加权患病率为31.7%(95%置信区间:28.7 - 34.8),而使用ACC/AHA新指南时相应患病率为45.6%(95%置信区间:43.0 - 48.3)。根据JNC7和ACC/AHA 2017年指南患有HTN的人群中,血压得到控制的比例分别为48.2%(95%置信区间:44.4 - 52.0)和21.0%(95%置信区间:18.1 - 24.2)。当使用两种指南评估血压时,40 - 59岁人群中HTN和CHTN患病率的最大绝对增幅分别为17.4%和30.0%。
鉴于未治疗的HTN引发并发症所带来的高疾病负担以及未治疗疾病的更高成本,新指南对于早期发现高危患者并预防不同人群中的并发症具有重要的公共卫生意义。