[变形性关节炎中来自人类关节软骨的胶原蛋白]
[Collagen from human joint cartilage in deforming arthritis].
作者信息
Volodina T T, Pechenova T N, Pliatsko V V, Stavinskiĭ Iu A, Shimanovskaia A K, Nosal' N A, Solodova E V
出版信息
Ukr Biokhim Zh (1978). 1991 Jul-Aug;63(4):47-51.
PMID:1949229
Abstract
Type II collagen of human cartilage has been comparatively studied in norm and at deforming arthrosis. Collagen preparations are characterized by aminoacid composition and electrophoretic mobility in polyacrylamide gel. It is supposed that at deforming arthrosis the degenerative-dystrophic processes in the articular cartilage of man are caused by appearance of procollagen.
摘要
对人类软骨的II型胶原蛋白在正常状态和变形性关节病状态下进行了比较研究。胶原蛋白制剂通过氨基酸组成和在聚丙烯酰胺凝胶中的电泳迁移率来表征。据推测，在变形性关节病中，人类关节软骨的退行性 - 营养不良过程是由前胶原蛋白的出现引起的。
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