Department of Nutritional Medicine, Interactive Research School for Health Affairs, Bharati Vidyapeeth University, Pune, India.
J Perinat Med. 2009;37(5):513-8. doi: 10.1515/JPM.2009.096.
To establish the levels of docosahexaenoic acid (DHA) and arachidonic acid (AA) in both plasma and erythrocytes of maternal and cord blood as well as in breast milk of mothers delivering babies at term.
A total of 148 mothers delivering babies at term were recruited from Bharati Medical Hospital, Pune, India.
Levels of DHA and AA in both plasma and erythrocyte were higher in cord blood compared to levels in maternal blood (P<0.001). Maternal plasma and erythrocyte DHA levels had a positive association with the respective levels in cord blood (P<0.001). However, such an association was not seen for AA levels. Maternal plasma omega 3 and omega 6 fatty acids were positively associated with the respective milk fatty acids (P<0.01).
Our results indicate that milk long-chain polyunsaturated fatty acids (LCPUFA) status reflects the concentrations of maternal LCPUFA in women delivering babies at term. Improving the maternal LCPUFA status throughout pregnancy and lactation may improve the milk LCPUFA status and ultimately benefit the infant.
建立足月分娩产妇母血、脐血和母乳中二十二碳六烯酸（DHA）和花生四烯酸（AA）的水平。
本研究共纳入了来自印度浦那市 Bharati 医疗医院的 148 名足月分娩产妇。
与母血相比，脐血中 DHA 和 AA 的水平均较高（P<0.001）。产妇血浆和红细胞 DHA 水平与脐血中的相应水平呈正相关（P<0.001）。然而，AA 水平没有观察到这种关联。产妇血浆 ω-3 和 ω-6 脂肪酸与相应的乳脂肪酸呈正相关（P<0.01）。
我们的研究结果表明，母乳长链多不饱和脂肪酸（LCPUFA）的状态反映了足月分娩产妇的母体 LCPUFA 浓度。在整个妊娠和哺乳期改善母体 LCPUFA 状态可能会改善母乳 LCPUFA 状态，并最终使婴儿受益。
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