复活节岛上美洲印第安人对波利尼西亚基因库贡献的更多证据。
Further evidence of an Amerindian contribution to the Polynesian gene pool on Easter Island.
作者信息
Thorsby E, Flåm S T, Woldseth B, Dupuy B M, Sanchez-Mazas A, Fernandez-Vina M A
机构信息
Institute of Immunology, Rikshospitalet University Hospital and University of Oslo, Oslo, Norway.
出版信息
Tissue Antigens. 2009 Jun;73(6):582-5. doi: 10.1111/j.1399-0039.2009.01233.x.
Available evidence suggests a Polynesian origin of the Easter Island population. We recently found that some native Easter Islanders also carried some common American Indian (Amerindian) human leukocyte antigen (HLA) alleles, which probably were introduced before Europeans discovered the island in 1722. In this study, we report molecular genetic investigations of 21 other selected native Easter Islanders. Analysis of mitochondrial DNA and Y chromosome markers showed no traces of an Amerindian contribution. However, high-resolution genomic HLA typing showed that two individuals carried some other common Amerindian HLA alleles, different from those found in our previous investigations. The new data support our previous evidence of an Amerindian contribution to the gene pool on Easter Island.
现有证据表明复活节岛居民起源于波利尼西亚。我们最近发现，一些复活节岛原住民也携带一些常见的美洲印第安人人类白细胞抗原（HLA）等位基因，这些等位基因可能在1722年欧洲人发现该岛之前就已传入。在本研究中，我们报告了对另外21名选定的复活节岛原住民的分子遗传学调查。线粒体DNA和Y染色体标记分析未显示美洲印第安人贡献的痕迹。然而，高分辨率基因组HLA分型显示，有两人携带一些其他常见的美洲印第安人HLA等位基因，与我们之前调查中发现的不同。这些新数据支持了我们之前关于美洲印第安人对复活节岛基因库有贡献的证据。
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