Hosoya Noriaki, Su Zhaohui, Wilkin Timothy, Gulick Roy M, Flexner Charles, Hughes Michael D, Skolnik Paul R, Giguel Françoise, Greaves Wayne L, Coakley Eoin, Kuritzkes Daniel R
Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
J Clin Microbiol. 2009 Aug;47(8):2604-6. doi: 10.1128/JCM.00632-09. Epub 2009 Jun 3.
Detection of CXCR4-using human immunodeficiency virus by the Trofile assay was compared to that by assays using virus isolates or replication-competent recombinants. Concordance with the Trofile assay was good, but assays using replicating viruses did not increase substantially the ability to detect the presence of CXCR4-using virus.
通过Trofile检测法检测使用CXCR4的人类免疫缺陷病毒,并与使用病毒分离株或具有复制能力的重组体的检测法进行比较。与Trofile检测法的一致性良好,但使用复制病毒的检测法并未显著提高检测使用CXCR4病毒存在的能力。