Taylor M A, Hunt K R, Wilson C A
Department of Parasitology, Central Veterinary Laboratory, Weybridge, Surrey.
Vet Rec. 1991 Aug 24;129(8):166-70. doi: 10.1136/vr.129.8.166.
The effectiveness of clean grazing systems for controlling the sheep abomasal parasite Haemonchus contortus under experimental conditions was monitored for a grazing season in ewes and lambs carrying either benzimidazole-susceptible or resistant populations of the parasite. Both preventive and evasive strategies failed to give effective control of H contortus. Lambs grazing with ewes that had received no anthelmintic showed clinical signs of haemonchosis by early July. Lambs from ewes dosed with a benzimidazole (mebendazole) before turn out, developed clinical signs of haemonchosis later in the season. The presence of anthelmintic resistant genotypes had a significant effect on the appearance of clinical signs, and on the epidemiology and control of disease. It was concluded that alternative worm control strategies will be required for the effective control of H contortus in the United Kingdom.
在一个放牧季节里,对携带苯并咪唑敏感或抗性寄生虫种群的母羊和羔羊,监测了清洁放牧系统在实验条件下控制绵羊皱胃寄生虫捻转血矛线虫的效果。预防和规避策略均未能有效控制捻转血矛线虫。与未接受驱虫药的母羊一起放牧的羔羊在7月初就出现了血矛线虫病的临床症状。产羔前用苯并咪唑(甲苯达唑)给药的母羊所产的羔羊,在季节后期出现了血矛线虫病的临床症状。抗驱虫药基因型的存在对临床症状的出现以及疾病的流行病学和控制有显著影响。得出的结论是,在英国,需要采用替代的蠕虫控制策略来有效控制捻转血矛线虫。