Jacobowitz D M
J Invest Dermatol. 1977 Jul;69(1):106-11. doi: 10.1111/1523-1747.ep12497906.
Recent information about the localization of sympathetic nerves and catecholamine-containing cells suggests sites of action not usually described in the neuroscience textbooks. In this study, we focused on the autonomic controls that affect ganglia, heart, gut, and chemoreceptors. As a result of some speculation derived mainly from histochemical observations and partially from physiologic data, we concluded that at the organ level the interplay between a nerve terminal-receptor serves as a local control. Additional controls may function at the ganglion level where catecholamine-containing chromaffin cells may serve as interneurons. We suggest that all peripheral catecholamine-containing elements which function in a modulatory role are not vital to the survival of the individual but rather serve as "fine tune" adjustment that do not involve the central nervous system.
近期有关交感神经和含儿茶酚胺细胞定位的信息表明了一些神经科学教科书中通常未描述的作用位点。在本研究中，我们聚焦于影响神经节、心脏、肠道和化学感受器的自主控制。基于主要来自组织化学观察且部分来自生理学数据的一些推测，我们得出结论，在器官水平，神经末梢与受体之间的相互作用起到局部控制的作用。在神经节水平可能存在其他控制机制，含儿茶酚胺的嗜铬细胞可能充当中间神经元。我们认为，所有起调节作用的外周含儿茶酚胺成分对个体生存并非至关重要，而是起到不涉及中枢神经系统的“微调”作用。
