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Antiepileptic medications in development.

作者信息

Graves N M, Leppik I E

机构信息

Department of Pharmacy Practice, College of Pharmacy, Minneapolis, MN 55455.

出版信息

DICP. 1991 Sep;25(9):978-86. doi: 10.1177/106002809102500913.

DOI:10.1177/106002809102500913
PMID:1949977
Abstract

Recently, there has been an increase in the research devoted to the study of investigational antiepileptic medications. This has led to extensive clinical trials of several new compounds. This review focuses on four of these antiepileptic medications in development: felbamate, gabapentin, lamotrigine, and vigabatrin. Each has a unique mechanism of action and great potential for the treatment of epilepsy.

摘要

相似文献

1
Antiepileptic medications in development.
DICP. 1991 Sep;25(9):978-86. doi: 10.1177/106002809102500913.
2
Antiepileptic drugs in development: prospects for the near future.正在研发的抗癫痫药物:近期前景
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Novel antiepileptic drugs: nursing implications.新型抗癫痫药物:护理要点
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The use of new antiepileptic medications in pediatric patients with epilepsy.
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Comparative pharmacokinetics of the newer antiepileptic drugs.新型抗癫痫药物的比较药代动力学
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Mechanisms of action of new antiepileptic drugs: rational design and serendipitous findings.
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[Advantages and disadvantages of new antiepileptic drugs].
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Pharmacokinetic profile of topiramate in comparison with other new antiepileptic drugs.托吡酯与其他新型抗癫痫药物相比的药代动力学概况。
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Pharmacokinetics of new antiepileptic drugs.新型抗癫痫药物的药代动力学
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Antiepileptic drugs in clinical development.处于临床开发阶段的抗癫痫药物。
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引用本文的文献

1
Topiramate. A review of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of epilepsy.托吡酯。其药效学和药代动力学特性以及在癫痫治疗中的临床疗效综述。
Drugs. 1997 Nov;54(5):752-73. doi: 10.2165/00003495-199754050-00009.
2
Gabapentin. A review of its pharmacological properties and clinical potential in epilepsy.加巴喷丁。其药理学特性及在癫痫治疗中的临床潜力综述。
Drugs. 1993 Sep;46(3):409-427. doi: 10.2165/00003495-199346030-00007.
3
Lamotrigine. A review of its pharmacological properties and clinical efficacy in epilepsy.
拉莫三嗪。其药理学特性及在癫痫治疗中的临床疗效综述。
Drugs. 1993 Jul;46(1):152-76. doi: 10.2165/00003495-199346010-00009.
4
Felbamate. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in epilepsy.非氨酯。对其药效学、药代动力学特性及癫痫治疗疗效的综述。
Drugs. 1993 Jun;45(6):1041-1065. doi: 10.2165/00003495-199345060-00008.
5
Zonisamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy.
Drugs. 1993 May;45(5):760-87. doi: 10.2165/00003495-199345050-00010.