Lumenta C B, Herdmann J, von Tempelhoff W, Hamacher J, Schüren M
Neurochirurgische Klinik der Heinrich-Heine-Universität Düsseldorf.
Zentralbl Neurochir. 1991;52(2):49-58.
This review article delineates the physiology and methodological principles of somatosensory (SEP) and motor evoked potentials (MEP), as well as our own results in 40 patients monitored during spinal surgery. In 29 patients an intraoperative SEP and in 15 patients a MEP monitoring was performed. Both modalities were applied in 4 patients. 19 patients had an intramedullary tumor, 15 patients had an intradural extramedullary tumor, 4 patients had an extradural mass lesion, and 2 patients had a spinal arteriovenous malformation. Technical problems with SEP monitoring occurred in 3 of 29 cases, problems with MEP monitoring occurred in 4 of 15 cases. Whereas anesthesia showed only little influence on SEP, an appropriate anesthesiological management was of major importance for MEP monitoring. Other factors, e.g. body temperature and blood pressure, also affected the evoked potentials. In all 35 patients in whom intraoperative SEP and/or MEP monitoring was successfully performed, evoked potentials showed a clear correlation with the initial postoperative neurological findings i.e. there were only cases of correct positive or correct negative monitoring. Transient evoked potential changes could always be attributed to surgical maneuvers. Our results show that intraoperative spinal cord monitoring with both SEP and MEP can supply helpful information on neural integrity. The choice of the evoked potential modality to be used and the choice of the sites of stimulation and recording depends on individual pathoanatomical findings and on the operative procedure required. Intraoperative evoked potential monitoring is indispensable during high risk spinal surgery such as surgery for intramedullary tumor or for mass lesions above C5.
这篇综述文章阐述了体感诱发电位(SEP)和运动诱发电位(MEP)的生理学及方法学原理,以及我们在40例脊柱手术监测患者中的自身研究结果。29例患者术中进行了SEP监测,15例患者进行了MEP监测。4例患者同时应用了这两种监测方式。19例患者患有髓内肿瘤,15例患者患有硬脊膜内髓外肿瘤,4例患者患有硬膜外肿块病变,2例患者患有脊柱动静脉畸形。29例SEP监测中有3例出现技术问题,15例MEP监测中有4例出现问题。麻醉对SEP影响较小,而合适的麻醉管理对MEP监测至关重要。其他因素,如体温和血压,也会影响诱发电位。在所有成功进行术中SEP和/或MEP监测的35例患者中,诱发电位与术后初期神经学检查结果呈现明显相关性,即只有监测结果正确阳性或正确阴性的病例。诱发电位的短暂变化总能归因于手术操作。我们的结果表明,术中同时使用SEP和MEP进行脊髓监测可为神经完整性提供有用信息。所选用的诱发电位监测方式以及刺激和记录部位的选择取决于个体病理解剖学发现和所需的手术操作。在高风险脊柱手术,如髓内肿瘤手术或C5以上肿块病变手术中,术中诱发电位监测是必不可少的。