Rusakova E V, Bezuglova M S, Vasil'eva V I, Frank K D, Drynov I D, Filatov N N, Demskiĭ V I
Zh Mikrobiol Epidemiol Immunobiol. 1991 Aug(8):51-4.
Basing on the results of seroepidemiological study, carried out in two districts of Moscow by different methods, cluster selection method including, the authors have developed the following recommendations aimed at improving the strategy of revaccination against measles: (1) selective revaccination of only seronegative children or those with poor antimeasles immunity should be carried out, thus making it possible to reduce the number of susceptible children and diminish the risk of postimmunization reactions and complications; (2) when determining the groups of children to be revaccinated and the age suitable for revaccination, one should bear in mind the specific local features of the epidemic process in measles and the morbidity values, as well as the data on antimeasles immunity in children of different age groups; (3) serologic monitoring of the quality and immunologic effectiveness of different batches of live measles vaccine permits timely removal of nonstandard batches from practical use, thus improving the efficacy of vaccinal prophylaxis of measles.
基于在莫斯科两个地区采用不同方法(包括整群抽样法)进行的血清流行病学研究结果,作者制定了以下旨在改进麻疹再接种策略的建议:(1)仅对血清阴性儿童或抗麻疹免疫力低下的儿童进行选择性再接种,从而有可能减少易感儿童数量,并降低免疫后反应和并发症的风险;(2)在确定要再接种的儿童群体和适合再接种的年龄时,应考虑麻疹流行过程的具体地方特点和发病率值,以及不同年龄组儿童的抗麻疹免疫力数据;(3)对不同批次的麻疹活疫苗的质量和免疫效果进行血清学监测,可及时将不合格批次从实际使用中剔除,从而提高麻疹疫苗预防的效果。