Pilger E, Obernosterer A, Stark G, Decrinis M
Medizinischen Universitätsklinik, Karl-Franzens-Universität Graz.
Acta Med Austriaca. 1991;18(3):68-72.
50% of all patients with deep venous thrombosis (DVT) are simultaneously suffering from other diseases, which might support or cause the thrombogenesis. In the other 50% no etiological factor can be identified. There are several factors predisposing to DVT, such as immobilisation, surgery, old age of the patient, estrogen treatment. These factors are risk factors but not etiological factors. DVT is not only initiated by the three main factors (hypercoagulability, stasis, endothelial lesion) already described by Virchow. A very complicated balance of several complex single systems (endothelium, vessel wall motion, thrombocytes, hemostatic and fibrinolytic systems with their inhibitors) has to be disturbed in order to initiate venous thrombosis.
所有深静脉血栓形成（DVT）患者中有50%同时患有其他疾病，这些疾病可能促进或导致血栓形成。在另外50%的患者中，无法确定病因。有几个因素易引发DVT，如固定不动、手术、患者高龄、雌激素治疗。这些因素是危险因素而非病因。DVT不仅由维尔肖已经描述的三个主要因素（高凝状态、血流淤滞、内皮损伤）引发。为了引发静脉血栓形成，必须打破几个复杂单一系统（内皮、血管壁运动、血小板、止血和纤维蛋白溶解系统及其抑制剂）之间非常复杂的平衡。
