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儿童A组链球菌坏死性筋膜炎的临床和微生物学特征

Clinical and microbiologic characteristics of group A streptococcal necrotizing fasciitis in children.

作者信息

Minodier Philippe, Bidet Philippe, Rallu Fabien, Tapiero Bruce, Bingen Edouard, Ovetchkine Philippe

机构信息

Department of Pediatrics, CHU Sainte-Justine, Montréal, Canada.

出版信息

Pediatr Infect Dis J. 2009 Jun;28(6):541-3. doi: 10.1097/inf.0b013e318195bb10.

DOI:10.1097/inf.0b013e318195bb10
PMID:19504739
Abstract

An increase in the incidence of Group A streptococcal necrotizing fasciitis has recently been observed in Montréal, Canada. Clinical features of children hospitalized for invasive Group A streptococcal infections and various virulence factor genes of the bacteria were concomitantly analyzed. It was determined that varicella and presence of speC gene in group A streptococcal strains were associated with necrotizing fasciitis.

摘要

最近在加拿大蒙特利尔观察到A组链球菌坏死性筋膜炎的发病率有所上升。对因侵袭性A组链球菌感染住院的儿童的临床特征以及该细菌的各种毒力因子基因进行了同步分析。结果确定,水痘和A组链球菌菌株中speC基因的存在与坏死性筋膜炎有关。

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