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一种用于研究眼肿瘤对人眼内部温度分布影响的边界元模型。

A boundary element model for investigating the effects of eye tumor on the temperature distribution inside the human eye.

作者信息

Ooi E H, Ang W T, Ng E Y K

机构信息

School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798, Singapore.

出版信息

Comput Biol Med. 2009 Aug;39(8):667-77. doi: 10.1016/j.compbiomed.2009.04.010. Epub 2009 Jun 7.

Abstract

A three-dimensional boundary element model of the human eye is developed to investigate the thermal effects of eye tumor on the ocular temperature distribution. The human eye is modeled as comprising several regions which have different thermal properties. The tumor is one of these regions. The thermal effects of the tumor are simulated by taking it to have a very high metabolic heat generation and blood perfusion rate. Inside the tumor, the steady state temperature is governed by the Pennes bioheat equation. Elsewhere, in normal tissues of the eye, the temperature satisfies the Laplace's equation. To compute the temperature on the corneal surface, the surface boundary of each region is divided into triangular elements.

摘要

开发了一种人眼的三维边界元模型,以研究眼肿瘤对眼内温度分布的热效应。人眼被建模为包含几个具有不同热特性的区域。肿瘤是这些区域之一。通过将肿瘤设定为具有非常高的代谢产热和血液灌注率来模拟肿瘤的热效应。在肿瘤内部,稳态温度由佩恩斯生物热方程控制。在其他地方,在眼睛的正常组织中,温度满足拉普拉斯方程。为了计算角膜表面的温度,将每个区域的表面边界划分为三角形单元。

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