[恶性外阴软组织肌上皮瘤]
[Malignant vulvar soft tissue myoepithelioma].
作者信息
mukhina M S, Maksimova N A, Safina N S, Chizh I A
出版信息
Arkh Patol. 2009 Mar-Apr;71(2):18-20.
PMID:19507572
Abstract
The authors describe a case of malignant vulvar soft tissue myoepithelioma in a 41-year-old woman. Microscopically, epithelioid and spindle cells were located in the myxoid stroma. Tumor cells co-expressed pan-cytokeratin, EMA, and cytokeratin 18, vimentin, protein S100, and smooth muscle actin. The tumor was found to have a very high proliferative activity (Ki-67 was as high as 80%). The disease was fulminant with a fatal outcome 4 months after the occurrence of the first symptoms of the tumor.
摘要
作者描述了一例41岁女性的恶性外阴软组织肌上皮瘤。显微镜下，上皮样细胞和梭形细胞位于黏液样基质中。肿瘤细胞共表达全细胞角蛋白、上皮膜抗原、细胞角蛋白18、波形蛋白、蛋白S100和平滑肌肌动蛋白。发现该肿瘤具有非常高的增殖活性（Ki-67高达80%）。该疾病进展迅速，在出现肿瘤的首发症状4个月后导致死亡。
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