肾脏中的高渗应激：一种必要的弊端。
Hypertonic stress in the kidney: a necessary evil.
作者信息
Kwon Min Seong, Lim Sun Woo, Kwon H Moo
机构信息
Department of Medicine, University of Maryland, Baltimore, MD, USA.
出版信息
Physiology (Bethesda). 2009 Jun;24:186-91. doi: 10.1152/physiol.00005.2009.
PMID:19509128
Abstract
The interstitium of the renal medulla is hypertonic, imposing deleterious effects on local cells. At the same time, the hypertonicity provides osmotic gradient for water reabsorption and is a local signal for tissue-specific gene expression and differentiation of the renal medulla, which is a critical organ for water homeostasis.
摘要
肾髓质的间质呈高渗状态，对局部细胞产生有害影响。与此同时，这种高渗性为水的重吸收提供了渗透梯度，并且是肾髓质组织特异性基因表达和分化的局部信号，而肾髓质是水稳态的关键器官。
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