Blostein Paul A, Plaisier Brian R, Maltz Sheldon B, Davidson Scott B, Wideman Eric W, Feucht Eric C, VandenBerg Sheri L
Trauma, Burn, and Surgical Critical Care Program, Bronson Methodist Hospital, Kalamazoo, Michigan 49007, USA.
J Trauma. 2009 Jun;66(6):1712-7; discussion 1717. doi: 10.1097/TA.0b013e3181a0e589.
To describe the thermal injuries related to methamphetamine (METH) production, characterize patients' courses, and compare patients with matched controls and to the previously published series.
Trauma registry data from January 2001 to November 2005 was retrospectively reviewed. METH patients were compared with other burn patients of similar age and total body surface area burn size for toxicology, injury extent, therapies, hospital course, outcomes, and hospital charges. The METH group was compared with the other published series of METH-related burn patients.
Twenty-nine patients (86.2% male) had METH-related burns. METH and control groups were similar in age, gender, predicted resuscitation fluid volume, and total body surface area. Mortality, mean length of stay, surgical procedures, and mean hospital charges did not differ significantly between the groups. Endotracheal intubation was required more frequently in METH patients (55.2% vs. 24.1%, p = 0.020). METH patients mean resuscitation volume was greater than controls (9,638 mL vs. 6,633 mL, p = 0.011), but neither group exceeded the volume predicted by the Parkland formula. More METH patients had inhalation injury (41.4% vs. 13.8%, p = 0.019). A METH patient was more likely to have a complication than his matched control (p = 0.049), and pneumonia was more frequent in the METH group (p = 0.005). Private insurance was less common in METH patients (10.3% vs. 58.6%, p < 0.001).
METH patients suffer more frequent inhalation injuries, need greater initial fluid resuscitation volume, require endotracheal intubation more frequently, and are more likely to have complications than matched controls. This does not translate to greater mortality, longer length of stay, more surgical procedures, or significantly greater hospital charges. Few METH patients hold private insurance.
描述与甲基苯丙胺（METH）生产相关的热烧伤情况，对患者病程进行特征分析，并将患者与匹配的对照组以及先前发表的系列病例进行比较。
回顾性分析2001年1月至2005年11月的创伤登记数据。将甲基苯丙胺患者与年龄和烧伤总面积相似的其他烧伤患者在毒理学、损伤程度、治疗方法、住院病程、结局和住院费用方面进行比较。将甲基苯丙胺组与其他已发表的甲基苯丙胺相关烧伤患者系列进行比较。
29例患者（86.2%为男性）发生了与甲基苯丙胺相关的烧伤。甲基苯丙胺组和对照组在年龄、性别、预计复苏液量和烧伤总面积方面相似。两组之间的死亡率、平均住院时间、手术操作和平均住院费用无显著差异。甲基苯丙胺患者需要气管插管的频率更高（55.2%对24.1%，p = 0.020）。甲基苯丙胺患者的平均复苏液量大于对照组（9638毫升对6633毫升，p = 0.011），但两组均未超过Parkland公式预测的液量。更多的甲基苯丙胺患者有吸入性损伤（41.4%对13.8%，p = 0.019）。甲基苯丙胺患者比匹配的对照组更易发生并发症（p = 0.049），且甲基苯丙胺组肺炎更常见（p = 0.005）。甲基苯丙胺患者中私人保险较少见（10.3%对58.6%，p < 0.001）。
与匹配的对照组相比，甲基苯丙胺患者吸入性损伤更频繁，初始液体复苏量更大，气管插管需求更频繁，且更易发生并发症。但这并未导致更高的死亡率、更长的住院时间、更多的手术操作或显著更高的住院费用。很少有甲基苯丙胺患者拥有私人保险。
