Zangos S, Müller C, Mayer F, Naguib N N, Nour-Eldin N-E A, Hansmann M-L, Herzog C, Hammerstingl R M, Thalhammer A, Mack M, Vogl T J, Eichler K
Institut für Diagnostische und Interventionelle Radiologie, J.-W.-Goethe-Universität Frankfurt.
Rofo. 2009 Jul;181(7):658-63. doi: 10.1055/s-0028-1109349. Epub 2009 Jun 10.
The purpose of this study was to evaluate the safety and clinical value of MR-guided biopsies in an open 0.2 T low-field system.
A total of 322 patients with suspicious lesions of different body regions were biopsied in a low-field MRI system (0.2 T, Concerto, Siemens). The procedures were guided using T 1-weighted Flash sequences (TR/TE = 100/9; 70 degrees). The lesions were repeatedly biopsied using the coaxial technique with a 15-gauge (diameter 2 mm) puncture needle. Complications and biopsy findings were analyzed retrospectively.
In all cases the biopsy procedures were successfully performed with MR guidance. In 298 patients diagnosis was able to be confirmed on the basis of the probes. The clinical follow-up showed that in 24 patients the lesions were missed by MR-guided biopsy. From this a sensitivity of 86%, a specificity of 87% and an accuracy of 93% were calculated. In two patients major complications were observed (morbidity rate 0.6 %).
MR-guided biopsy can be performed safely and precisely in a low-field MR system and are a supplement to US or CT-guided biopsies.
本研究旨在评估在开放式0.2T低场系统中进行磁共振引导活检的安全性和临床价值。
共有322例不同身体部位有可疑病变的患者在低场MRI系统(0.2T,西门子Concerto)中接受活检。操作采用T1加权快速成像序列(TR/TE = 100/9;70°)引导。使用同轴技术,用15号(直径2mm)穿刺针反复对病变进行活检。对并发症和活检结果进行回顾性分析。
所有病例均在磁共振引导下成功完成活检操作。298例患者的诊断可根据活检样本得以证实。临床随访显示,24例患者的病变在磁共振引导活检中被漏诊。由此计算出敏感性为86%,特异性为87%,准确性为93%。2例患者出现严重并发症(发病率0.6%)。
在低场磁共振系统中,磁共振引导活检可以安全、精确地进行,是超声或CT引导活检的补充。