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高剂量与低剂量琥珀胆碱的比较。

Comparison of high and low doses of suxamethonium.

作者信息

Stewart K G, Hopkins P M, Dean S G

机构信息

University Department of Anaesthesia, St James University Hospital, Leeds.

出版信息

Anaesthesia. 1991 Oct;46(10):833-6. doi: 10.1111/j.1365-2044.1991.tb09595.x.

DOI:10.1111/j.1365-2044.1991.tb09595.x
PMID:1951997
Abstract

In a double-blind study, 67 young adult patients undergoing anaesthesia for dental extractions were allocated at random to receive either 0.5 mg/kg or 1.5 mg/kg suxamethonium. A greater increase in arterial pressure was seen following induction in the 1.5 mg/kg group, although overall intubating conditions were similar in the two groups. Suxamethonium-associated muscle pains were significantly more common in the group which received the larger dose (p less than 0.05).

摘要

在一项双盲研究中,67名接受拔牙麻醉的年轻成年患者被随机分配,分别接受0.5毫克/千克或1.5毫克/千克的琥珀胆碱。1.5毫克/千克组诱导后动脉压升高更明显,尽管两组的总体插管条件相似。接受较大剂量组的琥珀胆碱相关肌肉疼痛明显更常见(p小于0.05)。

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