Daum R
MMW Munch Med Wochenschr. 1977 May 6;119(18):629-32.
The advances in the treatment of the Wilm's tumor have been made both surgically and in the conservative field. Extirpation through a lateral incision has given way to the broad transabdominal exposure. Inoperable tumors are very rare. Cytostatics like actinomycin D and vincristine are already applied intraoperatively. The choice of cytostatic and the duration of cytostatic therapy is adjusted to the intraoperative staging. The Society for Pediatric Oncology has worked out a modified plan of treatment in accordance with the growth of the tumor, in addition irradiation is applied according to the tumor staging. The results are stated as between 60 and 70%, the histology of the tumor and the age of the child, in addition to the growth of the tumor, being especially important.
肾母细胞瘤的治疗在手术和保守治疗领域均取得了进展。经侧切口切除已被广泛的经腹暴露所取代。无法手术切除的肿瘤非常罕见。术中已开始应用放线菌素D和长春新碱等细胞抑制剂。细胞抑制剂的选择和细胞抑制治疗的持续时间根据术中分期进行调整。小儿肿瘤学会已根据肿瘤的生长情况制定了改良治疗方案，此外还根据肿瘤分期进行放疗。结果显示治愈率在60%至70%之间，肿瘤的组织学类型、患儿年龄以及肿瘤的生长情况尤为重要。
