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在东非,白内障联合小梁切除术治疗晚期青光眼:视力和眼内压结果。

Combined cataract and trabeculectomy surgery for advanced glaucoma in East Africa; visual and intra-ocular pressure outcomes.

机构信息

Comprehensive Community Based Rehabilitation for Tanzania (CCBRT) Disability Hospital, Dar es Salaam, Tanzania.

出版信息

Eye (Lond). 2010 Apr;24(4):573-7. doi: 10.1038/eye.2009.132. Epub 2009 Jun 12.

Abstract

AIM

To investigate visual and intra-ocular pressure (IOP) outcomes of combined cataract and glaucoma surgery at a high-volume centre in East Africa carried out over a 1-year period (2006).

METHODS

A retrospective analysis of patient records.

RESULTS

A total of 163 patients were identified. Mean age was 67 years (SD 11, range 21-86 years) and 113 (69%) were men. Presenting visual acuity in the operated eye was 6/60 or worse in 135/163 (93%) and was <3/60 in 76 of 163 (47%) patients. Mean presenting IOP was 28 mm Hg (SD 9, range 12-60). Pre-operative cup disc ratios were 0.8 or worse in 131 of 163 (85%) patients. Phacotrabeculectomy (PT) was carried out in 130 (80%) cases, small incision cataract surgery trabeculectomy (SICST) in 10 (6.1%) cases, and extra-capsular cataract extraction trabeculectomy (ECCET) in 23 (14.1%) cases. In all, 107 (66%) attended for follow-up (mean interval 104 days, range: 6-390 years, SD 88) and at follow-up 75 (70%) patients had improved visual acuity pre-operatively. Pre-operative cup disc ratio of 0.9 or greater predicted failure to improve VA at follow-up (OR 4.0 95% confidence interval (CI) 1.30-12.1). Fifty-nine (62% (95%CI 52-71%)) patients had follow-up IOPs of 6-15 mm Hg and 82 (85% (95% CI 78-92%)) had follow-up IOPs of 6-20 mm Hg.

CONCLUSION

Combined surgery produces visual benefit for most patients with similar pressure control to pure trabeculectomy and is therefore a useful option in practises where follow-up may be doubtful.

摘要

目的

调查在东非一个高容量中心进行的为期一年(2006 年)的白内障合并青光眼手术的视力和眼内压(IOP)结果。

方法

对患者病历进行回顾性分析。

结果

共确定了 163 名患者。平均年龄为 67 岁(标准差 11,范围 21-86 岁),113 名(69%)为男性。在手术眼中,163 名患者中有 135 名(93%)的视力为 6/60 或更差,76 名(47%)患者的视力<3/60。平均术前眼压为 28mmHg(标准差 9,范围 12-60)。163 名患者中有 131 名(85%)术前杯盘比为 0.8 或更差。130 例(80%)患者行白内障超声乳化吸除联合小梁切除术(PT),10 例(6.1%)患者行小切口白内障手术小梁切除术(SICST),23 例(14.1%)患者行白内障囊外摘除联合小梁切除术(ECCET)。共有 107 名(66%)患者接受随访(平均随访时间 104 天,范围:6-390 天,标准差 88),随访时 75 名(70%)患者术前视力提高。术前杯盘比为 0.9 或更大预测随访时视力无法提高(OR 4.0,95%置信区间(CI)为 1.30-12.1)。59 名(62%(95%CI 52-71%))患者的随访眼压为 6-15mmHg,82 名(85%(95%CI 78-92%))患者的随访眼压为 6-20mmHg。

结论

联合手术为大多数患者带来了视力获益,其眼压控制与单纯小梁切除术相似,因此在随访可能存在疑问的情况下是一种有用的选择。

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