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尼日利亚北部的原发性开角型青光眼:就诊时的分期及治疗接受情况。

Primary open angle glaucoma in northern Nigeria: stage at presentation and acceptance of treatment.

作者信息

Abdull Mohammed M, Gilbert Clare C, Evans Jennifer

机构信息

Ophthalmology Department, Abubakar Tafawa Balewa University Teaching Hospital, Bauchi, Bauchi State, Nigeria.

International Centre for Eye Health, Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK.

出版信息

BMC Ophthalmol. 2015 Aug 22;15:111. doi: 10.1186/s12886-015-0097-9.

Abstract

BACKGROUND

To determine the stage of primary open angle glaucoma at presentation at a tertiary eye unit, to assess patient's knowledge of glaucoma and acceptance and subsequent adherence to treatment.

METHOD

Information collected prospectively on new glaucoma patients aged 30 or more years included distance from residence and what they knew about glaucoma and its treatment. Treatment offered took account of disease severity and socioeconomic factors. Reasons for not accepting surgery were recorded. At follow up intraocular pressure (IOP) was measured and adherence to medication assessed verbally. Four categories of severity were defined based on visual acuity and visual fields defects in the worse eye.

RESULTS

131 patients were recruited (mean age 52.8 years; 62% male). Most attended because of symptoms (70%). Mean IOP in affected eyes was 31.9+/-SD 12.4 and mean vertical cup:disc ratio was 0.8. 99 eyes (47%) had a visual acuity of light perception or worse. Risk factors for advanced/end-stage disease were age >50 years, living >10 km from the hospital, some awareness of glaucoma, not being literate, being unemployed and presenting with symptoms. In multivariable analysis older age and poor knowledge of glaucoma remained independent risk factors. 75 were offered trabeculectomy: five agreed but only one underwent surgery. Reasons for rejecting surgery were fear (37%), preferred medical treatment (27 %) and cost (15 %). 32/85 (24 %) participants started on topical medication attended follow up. 72% reported excellent compliance but only 56% of glaucomatous eyes had IOPs less than 21 mmHg.

CONCLUSIONS

To prevent glaucoma blindness strategies are required which promote earlier detection, with counselling to promote acceptance of and adherence to treatment.

摘要

背景

为确定在三级眼科中心就诊时原发性开角型青光眼的分期,评估患者对青光眼的认知、对治疗的接受程度及后续治疗依从性。

方法

前瞻性收集30岁及以上新诊断青光眼患者的信息,包括居住地距离以及他们对青光眼及其治疗的了解情况。所提供的治疗方案考虑了疾病严重程度和社会经济因素。记录不接受手术的原因。随访时测量眼压,并通过口头询问评估药物治疗依从性。根据较差眼的视力和视野缺损定义了四类严重程度。

结果

共招募了131例患者(平均年龄52.8岁;62%为男性)。大多数患者因症状就诊(70%)。患眼平均眼压为31.9±标准差12.4,平均垂直杯盘比为0.8。99只眼(47%)视力为光感或更差。晚期/终末期疾病的危险因素包括年龄>50岁、居住在距离医院>10公里处、对青光眼有一定了解、文盲、失业以及因症状就诊。多变量分析显示,年龄较大和对青光眼了解不足仍是独立危险因素。75例患者被建议行小梁切除术:5例同意,但仅1例接受手术。拒绝手术的原因包括恐惧(37%)、倾向药物治疗(27%)和费用(15%)。85例开始局部用药的参与者中有32例(24%)接受了随访。72%的患者报告依从性良好,但仅56%的青光眼患眼眼压低于21 mmHg。

结论

为预防青光眼致盲,需要制定促进早期发现的策略,并进行咨询以促进对治疗的接受和依从。

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