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[内镜检查在胃十二指肠溃疡出血并发症中的作用]

[The role of endoscopy in the hemorrhagic complications of gastroduodenal ulcer].

作者信息

Scamporrino A, De Petris U, Novelli G, Salvi F, Coletti M, Schillaci F, Stagnitti F, Accettella U

机构信息

Istituto di Clinica Chirurgica d'Urgenza e di Pronto Soccorso, Università degli studi La Sapienza, La Roma.

出版信息

Ann Ital Chir. 1991 Jan-Feb;62(1):45-52; discussion 52-3.

PMID:1952503
Abstract

The hemorrhage is a fairly frequent event in the evolution of the gastroduodenal peptic ulcer syndrome. The mortality rate has remained approximately unchanged, in spite of the progress in instrumental diagnosis and medical therapy, in the last decade. The authors examine 163 cases of digestive hemorrhage from gastroduodenal ulcers, observed in the last five years (1984-1988), with particular reference to the medical or surgical treatment undertaken, and to the mortality rate. Gastroduodenal ulcers, in 340 cases of upper digestive hemorrhage, represented nearly half the lesions, registered in the same period. Duodenal ulcers (D.U.), were found in 124 patients (34.4%) and gastric ulcers (G.U.) in 39 patients (11.47%), 113 (91.1%) patients with D.U., and 33 (84.6%) patients with G.U. were treated by medical therapy. The mortality rate in this group was 6.16%. II patients (8.9%) with D.U. and 6 patients (15.3%) with G.U. were operated on. The surgical mortality rate was high at 35.2%. Total mortality rate was 9.2%. The endoscopic exam was useful for diagnostic bleeding investigation and contributed to therapeutic decisions. Active bleeding lesions were found in 38.4% of patients with G.U. and in 32.3% with D.U. In 61.6% of patients with G.U. and in 67.7% with D.U., the lesions had already stopped bleeding; but in both lesions nearly 40% of cases, presented signs of a recent hemorrhage. The prognosis and natural history of the hemorrhage, was not changed by an immediate exam. The clinical reports and the data furnished, especially from continuous bleeding and rebleeding lesions, could be useful in identifying a sub-group of patients who could obtain better results by surgical treatment within a suitable time. The endoscopy, besides selecting and contributing to a better therapeutic strategy, through haemostasis technic, could reduce mortality rate from gastroduodenal ulcer lesions.

摘要

出血是胃十二指肠消化性溃疡综合征发展过程中相当常见的事件。尽管在过去十年中仪器诊断和药物治疗取得了进展,但死亡率仍大致保持不变。作者研究了过去五年(1984 - 1988年)观察到的163例胃十二指肠溃疡引起的消化道出血病例,特别提及所采取的内科或外科治疗以及死亡率。在340例上消化道出血病例中,胃十二指肠溃疡占同期登记病变的近一半。发现124例患者患有十二指肠溃疡(D.U.)(34.4%),39例患者患有胃溃疡(G.U.)(11.47%),113例(91.1%)十二指肠溃疡患者和33例(84.6%)胃溃疡患者接受了内科治疗。该组的死亡率为6.16%。12例(8.9%)十二指肠溃疡患者和6例(15.3%)胃溃疡患者接受了手术治疗。手术死亡率高达35.2%。总死亡率为9.2%。内镜检查有助于诊断出血情况并为治疗决策提供依据。在38.4%的胃溃疡患者和32.3%的十二指肠溃疡患者中发现有活动性出血病变。在61.6%的胃溃疡患者和67.7%的十二指肠溃疡患者中,病变已经停止出血;但在这两种病变中,近40%的病例有近期出血迹象。立即检查并未改变出血的预后和自然病程。临床报告和所提供的数据,特别是来自持续出血和再出血病变的数据,有助于识别出一组患者,他们在合适的时间内通过手术治疗可能会获得更好的结果。内镜检查除了通过止血技术选择并有助于制定更好的治疗策略外,还可以降低胃十二指肠溃疡病变的死亡率。

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