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甲状腺半侧发育不全伴格雷夫斯病、格雷夫斯眼病和结节性甲状腺肿。

Thyroid hemiagenesis with Graves' disease, Graves' ophthalmopathy and multinodular goiter.

作者信息

Cakir Mehtap, Gonen Sait, Dikbas Oguz, Ozturk Banu

机构信息

Division of Endocrinology and Metabolism, Selcuk University, Meram School of Medicine, Konya, Turkey.

出版信息

Intern Med. 2009;48(12):1047-9. doi: 10.2169/internalmedicine.48.1984. Epub 2009 Jun 15.

Abstract

Thyroid hemiagenesis is a rare congenital anomaly in which one of the thyroid lobes with or without isthmus fails to develop. Here we present a woman patient with thyroid hemiagenesis, Graves' disease and ophthalmopathy with nodular goiter. Fine needle aspiration biopsy of the dominant nodule was suspicious of malignancy. The patient was referred for surgery for total thyroidectomy. Histopathological examination of the surgical material revealed benign features. The present case confirms that, although rare, a number of concomitant thyroid disorders can exist in a single patient with thyroid hemiagenesis just as it is seen for a normally developed thyroid gland.

摘要

甲状腺半侧缺如是一种罕见的先天性异常,其中甲状腺的一个叶(有或无峡部)未能发育。在此,我们报告一名患有甲状腺半侧缺如、格雷夫斯病、结节性甲状腺肿伴眼病的女性患者。对主要结节进行细针穿刺活检怀疑为恶性。该患者被转诊接受甲状腺全切除术。手术标本的组织病理学检查显示为良性特征。本病例证实,尽管罕见,但甲状腺半侧缺如的单一患者可能存在多种并存的甲状腺疾病,就如同正常发育的甲状腺一样。

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