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[胰岛素对心肌对氢化可的松反应性的影响]

[Effect of insulin on the reactivity of the myocardium to hydrocortisone].

作者信息

Sviriakin V T, Kosmach P I

出版信息

Probl Endokrinol (Mosk). 1976 Jul-Aug;22(4):58-60.

PMID:195280
Abstract

Experiments were conducted on rats. A study was made (with the aid of histological and histochemical methods) of the effect of administration of hydrocortisone, insulin, and also of the combined administration of these hormones on the myocardial structure and metabolism. Hydrocortisone administration for 30 days proved to derange the metabolism and to cause dystrophic changes in the myocardium. In combined administration of hydrocortisone and insulin these dystrophic changes were much less pronounced.

摘要

在大鼠身上进行了实验。(借助组织学和组织化学方法)研究了氢化可的松、胰岛素的给药效果,以及这些激素联合给药对心肌结构和代谢的影响。结果表明,连续30天给予氢化可的松会扰乱代谢并导致心肌发生营养不良性变化。在氢化可的松和胰岛素联合给药时,这些营养不良性变化则明显减轻。

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