碘克沙醇诱发的急性泛发性脓疱性银屑病：一例报告。
Ioversol-induced acute generalized exanthematous pustulosis: a case report.
作者信息
Hammerbeck Ashley A, Daniels Natalie H, Callen Jeffrey P
机构信息
Division of Dermatology, Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
出版信息
Arch Dermatol. 2009 Jun;145(6):683-7. doi: 10.1001/archdermatol.2009.100.
BACKGROUND
Acute generalized exanthematous pustulosis (AGEP) is a relatively rare exfoliative dermatosis consisting of a generalized eruption of sterile, nonfollicular pustules arising on widespread erythematous and edematous skin that is usually caused by drugs. It has an acute onset, and patients often have systemic manifestations, including leukocytosis, fever, and hemodynamic instability. Rarely has AGEP been associated with radiocontrast dyes.
OBSERVATIONS
We describe an 84-year-old man who developed AGEP on 2 separate occasions after receiving an infusion of an ioversol-containing radiocontrast dye. Conclusion Acute generalized exanthematous pustulosis may occur after the use of intravenous radiocontrast dye.
背景
急性泛发性脓疱病（AGEP）是一种相对罕见的剥脱性皮肤病，表现为在广泛的红斑和水肿皮肤上出现全身性无菌性、非毛囊性脓疱疹，通常由药物引起。该病起病急，患者常伴有全身症状，包括白细胞增多、发热和血流动力学不稳定。急性泛发性脓疱病与放射造影剂相关的情况极为罕见。
观察
我们描述了一名84岁男性，在接受含碘海醇的放射造影剂输注后，两次分别发生了急性泛发性脓疱病。结论：使用静脉放射造影剂后可能发生急性泛发性脓疱病。
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