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骨髓移植背景下的呼吸道合胞病毒及其他呼吸道病毒

Respiratory syncytial virus and other respiratory viruses in the setting of bone marrow transplantation.

作者信息

Ison Michael G

机构信息

Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

出版信息

Curr Opin Oncol. 2009 Mar;21(2):171-6. doi: 10.1097/CCO.0b013e328324bc1c.

Abstract

PURPOSE OF REVIEW

Several epidemiologic studies have enhanced our understanding of the impact of respiratory viruses on bone marrow transplant recipients.

RECENT FINDINGS

Respiratory viral infections occur frequently following stem cell transplantation but present atypically. Many patients have asymptomatic infections. There is a growing armamentarium of antiviral agents currently under development, although prospective studies in transplant patients are needed.

SUMMARY

Respiratory viral infections occur frequently after hematopoietic stem cell transplant. Newer agents may prove useful in the prevention and treatment of respiratory viral infections in this population.

摘要

综述目的

多项流行病学研究增进了我们对呼吸道病毒对骨髓移植受者影响的理解。

最新发现

干细胞移植后呼吸道病毒感染频繁发生,但表现不典型。许多患者有无症状感染。目前正在研发的抗病毒药物越来越多,不过仍需要在移植患者中开展前瞻性研究。

总结

造血干细胞移植后呼吸道病毒感染很常见。新型药物可能对预防和治疗该人群的呼吸道病毒感染有用。

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