Zaĭrat'iants O V, Vetshev P S, Ippolitov I Kh, Shkrob L O, Belokrinitskiĭ D V, Khodzhaev Z Sh, Radenska-Lopovok S G
Arkh Patol. 1991;53(8):22-7.
The thymus is studied morphologically in 139 cases of myasthenia (with no thymic neoplasia). Hyperplasia of true thymic parenchyma (without its intralobular perivascular spaces) was observed in 28%, no change in 40% and atrophy in 32% of cases. Two types of the disease were distinguished on the basis of morphological and clinico-immunological parameters: the 1st type with a hyperplastic or normal thymic parenchyma and the 2nd type with its atrophy. These types probably differ in their pathogenesis. The outcome of the thymectomy in patients with the 1st type of myasthenia is most favourable, while in patients with the 2nd type the outcome in 42% of patients is either satisfactory or unfavourable.
对139例重症肌无力患者（无胸腺肿瘤）的胸腺进行了形态学研究。在28%的病例中观察到真正胸腺实质（不包括小叶内血管周围间隙）增生，40%的病例无变化，32%的病例出现萎缩。根据形态学和临床免疫学参数区分出两种类型的疾病：第1型为胸腺实质增生或正常，第2型为胸腺萎缩。这两种类型的发病机制可能不同。第1型重症肌无力患者胸腺切除的效果最为理想，而第2型患者中42%的患者手术效果为满意或不理想。
