Wilson N, Ashawesh K, Kulambil Padinjakara R N, Anwar A
Warwickshire Institute for Study of Diabetes, Endocrinology and Metabolism, University Hospital of Coventry and Warwickshire, Coventry CV2 2DX, UK.
Exp Clin Endocrinol Diabetes. 2009 Oct;117(9):486-9. doi: 10.1055/s-0029-1214426. Epub 2009 Jun 17.
Gestational Diabetes Mellitus (GDM) is associated with an increased the risk of maternal and foetal complications in pregnancy. However, these complications can significantly be reduced if GDM is detected early and treated. Recently published NICE guidelines recommended that GDM should be managed in a specialist joint endocrinology-diabetes clinic; dietary/lifestyle advice should be given, 1 h postprandial blood glucose should be monitored, and glycaemic control should be assessed by a diabetic care team. In the University Hospital Coventry and Warwickshire (UHCW) NHS Trust these measures were introduced between 2003 and 2005. This article describes the results of an audit comparing the maternal and foetal outcomes for 2 cohorts of patients with GDM treated in the UHCW Trust in 2000-2 and 2006-8. Between 2000-2 and 2006-8 there was a significant reduction in mean maternal glycosylated haemoglobin (HbA1c) in trimester 3 of pregnancy, mean foetal birth weight and neonatal admission rate to the special care baby unit (SCBU). This evidence suggests that introduction of the measures recommended by NICE can effect significant improvement in maternal glycaemic control and foetal outcomes.
妊娠期糖尿病(GDM)与孕期母婴并发症风险增加相关。然而,如果GDM能早期被发现并得到治疗,这些并发症可显著减少。最近发布的英国国家卫生与临床优化研究所(NICE)指南建议,GDM应在专业的内分泌 - 糖尿病联合诊所进行管理;应提供饮食/生活方式建议,监测餐后1小时血糖,并由糖尿病护理团队评估血糖控制情况。在考文垂与沃里克郡大学医院(UHCW)国民保健服务信托基金中,这些措施于2003年至2005年期间开始实施。本文描述了一项审计结果,该审计比较了2000 - 2年和2006 - 年在UHCW信托基金接受治疗的两组GDM患者的母婴结局。在2000 - 2年至2006 - 年期间,妊娠晚期孕妇平均糖化血红蛋白(HbA1c)、胎儿平均出生体重以及新生儿入住特殊护理婴儿病房(SCBU)的比率均显著降低。这一证据表明,采用NICE推荐的措施可显著改善孕妇血糖控制及胎儿结局。