Phillips P K, Dawson P J, Delderfield A J
National Institute for Biological Standards and Control, South Mimms, Herts, U.K.
Biologicals. 1991 Jul;19(3):219-21. doi: 10.1016/1045-1056(91)90038-l.
A capillary device has been developed to enable biological materials to be freeze-dried from aqueous and non-aqueous solution in ampoules conforming to DIN 58377-B5-fl. This device reduced the absorption of atmospheric moisture by the material and the diffusion of oxygen into the ampoules awaiting sealing, by a factor of 13 and 7, respectively, over a 30 min period, respectively, compared to unprotected ampoules. The device has the advantage of being able to be assembled and fitted to the ampoules mechanically.
