Department of Diagnostic and Interventional Radiology, University of Ulm, Germany.
Eur J Radiol. 2010 Nov;76(2):177-9. doi: 10.1016/j.ejrad.2009.05.045. Epub 2009 Jun 21.
The purpose of this study was to investigate the potential correlation between the size of the cisterna chyli (CC) and the tumor size in patients with malignancies on computed tomography (CT).
Out of a 3000 patient cohort 138 patients with histologically confirmed malignant disease, a detectable CC on CT and at least two CT scans within a 6 month period were included in this retrospective study. Out of 525 scans a total of 711 lesion intervals were evaluated. The volume of the CC and all target lesions (up to three per scan) were recorded. The Pearson correlation coefficient for the two parameters of changes in lesion size and CC size was calculated for the whole cohort and for a 33 patient subgroup that included only patients with tumors that showed the closest association with large CC in a previous study.
The mean difference in lesion size for all 711 intervals was -1165μl. The mean difference in CC size for all 711 intervals was -46.6μl. The respective Pearson correlation coefficient was .05 with a non-significant p-value of .1823 (subgroup: r=.04, p=.6358).
No significant correlation between the progression or regression of malignant disease and the size of the cisterna chyli could be found.
本研究旨在探讨在计算机断层扫描（CT）上患有恶性肿瘤的患者，其大网膜囊（CC）的大小与肿瘤大小之间的潜在相关性。
在 3000 名患者队列中，纳入了 138 名经组织学证实患有恶性疾病、在 CT 上可检测到 CC 且在 6 个月内至少有两次 CT 扫描的患者。在 525 次扫描中，共评估了 711 个病变间隔。记录 CC 和所有目标病变（每个扫描最多三个）的体积。计算了整个队列和先前研究中与大 CC 关联最密切的仅包括肿瘤患者的 33 名患者亚组中，病变大小和 CC 大小变化的两个参数之间的 Pearson 相关系数。
711 个间隔的病变大小平均差异为-1165μl。711 个间隔的 CC 大小平均差异为-46.6μl。相应的 Pearson 相关系数为.05，p 值为非显著的.1823（亚组：r=.04，p=.6358）。
未发现恶性疾病的进展或消退与大网膜囊大小之间存在显著相关性。
