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Dysregulation of positive transcription elongation factor B and myocardial hypertrophy.

作者信息

Rice Andrew P

出版信息

Circ Res. 2009 Jun 19;104(12):1327-9. doi: 10.1161/CIRCRESAHA.109.200485.

Abstract
摘要

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Phosphatase PPM1A regulates phosphorylation of Thr-186 in the Cdk9 T-loop.
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The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation.
EMBO J. 2008 Jul 9;27(13):1907-18. doi: 10.1038/emboj.2008.121. Epub 2008 Jun 19.
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Cell. 2007 Jul 13;130(1):77-88. doi: 10.1016/j.cell.2007.05.042.
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The RNA polymerase II CTD kinase Ctk1 functions in translation elongation.
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