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儿童腐蚀性物质摄入。

Caustic ingestions in children.

机构信息

Department of Pediatric Gastroenterology and Nutrition, Children's Hospital, Cleveland Clinic, Cleveland, Ohio 44195, USA.

出版信息

Curr Opin Pediatr. 2009 Oct;21(5):651-4. doi: 10.1097/MOP.0b013e32832e2764.

Abstract

PURPOSE OF REVIEW

The purpose of this review is to outline the current epidemiology, mechanism of injury, clinical manifestations, management and long-term complications of caustic ingestions in pediatric patients.

RECENT FINDINGS

Recent data suggest that more than 200 000 exposures to household or industrial cleaning products occur annually in the United States. It is difficult to determine what fraction of these exposures represents caustic ingestions. Caustic ingestions occur most commonly in children less than age 6 years. Because of the accidental nature of the ingestions, the case fatality rate for pediatric patients is significantly less than that of adolescents and adults. Despite laws to limit the concentration of household cleaning products, farm and industrial products and products stored in nonoriginal containers represent a significant source of caustic agents. Endoscopy remains the preferred method of staging injury. In children the absence of symptoms does not predict lack of relevant injury. However, the presence of three or more symptoms is associated with a high likelihood of significant injury. Long-term complications in pediatric patients may be severe and include esophageal cancer.

SUMMARY

Caustic ingestions remain a significant cause of pediatric morbidity in the United States and abroad. Endoscopy is the primary method of staging injury following a caustic ingestion. Extent of injury at initial evaluation remains the best predictor of morbidity and mortality in pediatric patients following an accidental caustic ingestion.

摘要

目的综述

本文旨在概述小儿腐蚀性摄入物的当前流行病学、损伤机制、临床表现、处理方法和长期并发症。

最新发现

最近的数据表明,美国每年有超过 20 万例家庭或工业清洁产品暴露。很难确定这些暴露中有多少是腐蚀性摄入物。腐蚀性摄入物最常见于 6 岁以下的儿童。由于摄入物是意外发生的,小儿患者的病死率明显低于青少年和成人。尽管有法律限制家用清洁产品、农场和工业产品以及储存在非原容器中的产品的浓度,但这些产品仍然是腐蚀性物质的重要来源。内镜检查仍然是评估损伤的首选方法。在儿童中,无症状并不能预测没有相关损伤。然而,存在三个或更多症状与严重损伤的高度可能性相关。小儿患者的长期并发症可能很严重,包括食管癌。

总结

腐蚀性摄入物仍然是美国和国外小儿发病率的一个重要原因。内镜检查是腐蚀性摄入物后评估损伤的主要方法。在初始评估时损伤的程度仍然是预测意外腐蚀性摄入物后小儿患者发病率和死亡率的最佳指标。

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