Celik Handan, Tosun Midraci, Cetinkaya Mehmet Bilge, Bektab Ahmet, Malatyalýodlu Erdal
Department of Obstetrics and Gynecology, Ondokuz Mayys University, Samsun, Turkey.
J Matern Fetal Neonatal Med. 2009 Aug;22(8):705-7. doi: 10.1080/14767050802702323.
In normal pregnancy, although maternal serum alkaline phosphatase increases and reaches the two-fold of non-pregnant serum level, above this level, hepatic, renal, osteal diseases and malignancies should be kept in mind. We report a case of 28-year-old pregnant woman with increased maternal serum level of alkaline phosphatase activity (17-fold) due to an increased level of placental isozyme. She delivered vaginally a healthy female baby. After delivery, maternal serum alkaline phosphatase activity returned to normal reference range. The aim of this case report is to show this exaggerated isozyme activity of alkaline phosphatase in pregnancy, and to differentiate it from other causes of elevated level of alkaline phosphatase.
在正常妊娠期间，尽管母体血清碱性磷酸酶升高并达到非妊娠血清水平的两倍，但高于此水平时，应考虑肝脏、肾脏、骨骼疾病和恶性肿瘤。我们报告一例28岁孕妇，其母体血清碱性磷酸酶活性水平升高（17倍）是由于胎盘同工酶水平升高所致。她经阴道分娩出一名健康女婴。分娩后，母体血清碱性磷酸酶活性恢复到正常参考范围。本病例报告的目的是展示妊娠期间碱性磷酸酶这种过度的同工酶活性，并将其与碱性磷酸酶水平升高的其他原因区分开来。
