Nordt Sean Patrick, Wu Jerry, Zahller Stephen, Clark Richard F, Cantrell F Lee
Division of Medical Toxicology and Department of Emergency Medicine, University of California, San Diego, San Diego, California 92103-8925, USA.
J Emerg Med. 2011 Apr;40(4):397-9. doi: 10.1016/j.jemermed.2009.05.004. Epub 2009 Jul 9.
Palytoxin is most commonly reported after ingestion of seafood. We report a case of palytoxin poisoning from dermal absorption with local toxicity from zoanthid coral in a patient with intact skin.
A 25-year-old previously healthy woman handled a zoanthid coral from a home aquarium without any barrier protection. The patient manifested neurologic symptoms of perioral paresthesia and dysguesia. In addition, there was local dermatologic toxicity that persisted for several days. The patient was treated supportively with corticosteroids and a histamine antagonist.
We report a case of palytoxin poisoning from dermal absorption after handling a zoanthid coral. Palytoxin is a potent marine toxin that affects the sodium-potassium ATPase (adenosinetriphosphatase) pump and can cause multiple clinical effects, including paresthesia, dysguesia, hypertension, respiratory depression, coma, and death.
摄入海鲜后最常报告出现岩沙海葵毒素中毒。我们报告一例皮肤完整的患者因接触纽扣珊瑚经皮肤吸收岩沙海葵毒素并出现局部毒性反应的病例。
一名25岁既往健康的女性在没有任何防护措施的情况下处理自家水族箱中的纽扣珊瑚。患者出现口周感觉异常和味觉障碍等神经症状。此外，还存在持续数天的局部皮肤毒性反应。患者接受了皮质类固醇和组胺拮抗剂的支持治疗。
我们报告一例接触纽扣珊瑚后经皮肤吸收岩沙海葵毒素中毒的病例。岩沙海葵毒素是一种强效海洋毒素，可影响钠钾ATP酶泵，并可导致多种临床效应，包括感觉异常、味觉障碍、高血压、呼吸抑制、昏迷和死亡。
