Reiss Nils, Schuett Ulrich, Maleszka Ariane, Kleikamp Georg, Schenk Soren, Gummert Jan
Clinic for Thoracic and Cardiovascular Surgery, Heart Center North Rhine-Westphalia, Ruhr-University of Bochum, Bad Oeynhausen, Germany.
Heart Surg Forum. 2009 Jun;12(3):E143-6. doi: 10.1532/HSF98.20091041.
Interventional closures of atrial septal defects (ASDs) and paravalvular leaks represent attractive treatment options to prevent surgical procedures. Nevertheless, a small number of complications or pitfalls remain after interventional closure of ASDs or paravalvular leaks that require surgical therapy. We report on 3 cases in which surgery was necessary after attempts to close a paravalvular leak. A mechanical valve prosthesis in the mitral position was explanted from a 73-year-old man because of increasing hemolysis and restriction of the motion of one leaflet by the occluder device. A 21-year-old woman with 3 previous surgeries for truncus arteriosus communis type 1 developed paravalvular leakage after replacements of the pulmonary and aortic valves. Although aortic insufficiency was reduced to grade I by placing 2 Amplatzer occluders, significant hemolysis developed. A 24-year-old woman had previously undergone 3 cardiac surgeries (commissurotomy at the age of 5 years for aortic stenosis, followed by aortic valve replacements at 13 and 14 years of age). The patient developed severe hemolysis after interventional closure. A redo aortic valve replacement was performed for the fourth time. As in the previous 2 cases, the surgery for this challenging case and the postoperative course went well. We also present 6 cases in which the occluder was explanted because of dislocation, thrombus formation, irritation of the aortic root, or systemic allergic reaction to the percutaneous occluder after initial closure of the ASD. The intra- and postoperative courses were uneventful in all cases. In summary, surgery for complications or pitfalls after interventional closure of paravalvular leaks or ASDs is challenging and carries a high risk in cases of paravalvular leaks. Nevertheless, the outcomes of the presented cases were uneventful. In the future, the development of a more suitable device technology may improve the results of interventional procedures, especially in cases of paravalvular leaks.
房间隔缺损(ASD)和瓣周漏的介入封堵术是预防外科手术的有吸引力的治疗选择。然而,在房间隔缺损或瓣周漏的介入封堵术后仍存在少数需要外科治疗的并发症或陷阱。我们报告3例在尝试封堵瓣周漏后需要进行手术的病例。一名73岁男性因溶血加重和封堵器装置限制一个瓣叶运动而取出二尖瓣位的机械瓣膜假体。一名21岁女性曾因I型共同动脉干接受过3次手术,在更换肺动脉瓣和主动脉瓣后出现瓣周漏。尽管通过放置2个Amplatzer封堵器使主动脉瓣关闭不全减轻至I级,但仍出现了明显的溶血。一名24岁女性曾接受过3次心脏手术(5岁时因主动脉狭窄行二尖瓣交界切开术,随后在13岁和14岁时行主动脉瓣置换术)。该患者在介入封堵后出现严重溶血,第四次进行了主动脉瓣置换术。与前2例一样,该具有挑战性病例的手术及术后过程顺利。我们还介绍了6例在房间隔缺损初始封堵后因封堵器脱位、血栓形成、主动脉根部刺激或对经皮封堵器的全身过敏反应而取出封堵器的病例。所有病例的术中及术后过程均顺利。总之,房间隔缺损或瓣周漏介入封堵术后并发症或陷阱的手术具有挑战性,在瓣周漏病例中风险较高。然而,所报告病例的结果均顺利。未来,开发更合适的器械技术可能会改善介入手术的结果,尤其是在瓣周漏病例中。