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[外科瓣膜置换术后瓣周漏:经皮减少瓣周漏是否有作用?]

[Paravalvular leak following surgical valve replacement: is there a role for percutaneous paravalvular leak reduction?].

作者信息

Noble S, lbrahim R, Basmadjian A, Müller H, Lerch R, Roffi M

机构信息

Service de cardiologie, Départment de médecine, HUG, Genève.

出版信息

Rev Med Suisse. 2010 Jun 2;6(251):1154-8.

Abstract

After valve replacement, significant paravalvular leaks (PVL) may develop in up to 12.5% of the cases. Signs and symptoms include congestive heart failure and/or haemolysis and therefore may require reintervention. Redo valve surgery is considered the therapy of choice for symptomatic patients, either by valve replacement or leak repair. Considering the risk of morbidity and mortality associated with a surgical reintervention and the high post-surgical recurrence of PVL, the endovascular treatment represents an attractive alternative to surgery for high risk patients. The percutaneous approach aims at PVL reduction by implantation of certain occluder devices. The procedure is technically feasible in 60 to 90% of the cases according to different series. Technical success is associated with clinical improvement in 50 to 80% of the cases.

摘要

瓣膜置换术后,高达12.5%的病例可能会出现明显的瓣周漏(PVL)。体征和症状包括充血性心力衰竭和/或溶血,因此可能需要再次干预。再次瓣膜手术被认为是有症状患者的首选治疗方法,可通过瓣膜置换或漏口修复来进行。考虑到手术再次干预相关的发病和死亡风险以及PVL术后的高复发率,血管内治疗对于高危患者而言是一种有吸引力的手术替代方案。经皮方法旨在通过植入某些封堵装置来减少PVL。根据不同系列报道,该手术在60%至90%的病例中技术上是可行的。50%至80%的病例中,技术成功与临床改善相关。

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