多发性硬化症。动物模型：小鼠感染泰勒氏病毒 - Suppr

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超能文献

Multiple sclerosis. Animal model:Theiler's virus infection in mice.

作者信息

Dal Canto M C, Lipton H L

出版信息

Am J Pathol. 1977 Aug;88(2):497-500.

PMID:195474

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2032181/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/2032181/8bdc18f3c4a6/amjpathol00396-0249-a.jpg

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Multiple sclerosis. Animal model:Theiler's virus infection in mice.多发性硬化症。动物模型：小鼠感染泰勒氏病毒

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Induction of Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease in genetically resistant mice.在基因抗性小鼠中诱导泰勒氏鼠脑脊髓炎病毒（TMEV）诱发的脱髓鞘疾病。

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Infection of a β-galactosidase-deficient mouse strain with Theiler's murine encephalomyelitis virus reveals limited immunological dysregulations in this lysosomal storage disease.用泰勒氏鼠脑脊髓炎病毒感染β-半乳糖苷酶缺陷型小鼠品系，揭示了这种溶酶体贮积病中有限的免疫失调。

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本文引用的文献

Observations on encephalomyelitis of mice (DA strain).对小鼠（DA品系）脑脊髓炎的观察

J Exp Med. 1952 Dec;96(6):517-30. doi: 10.1084/jem.96.6.517.

Prevalence of viruses in mouse colonies.小鼠群体中病毒的流行情况。

Natl Cancer Inst Monogr. 1966 Feb;20:25-45.

Viral infections and demyelinating diseases.病毒感染与脱髓鞘疾病。

N Engl J Med. 1973 May 24;288(21):1103-10. doi: 10.1056/NEJM197305242882106.

Primary demyelination in Theiler's virus infection. An ultrastructural study.泰勒氏病毒感染中的原发性脱髓鞘。一项超微结构研究。

Lab Invest. 1975 Dec;33(6):626-37.

Theiler's virus-induced demyelination: prevention by immunosuppression.泰勒氏病毒诱导的脱髓鞘：通过免疫抑制预防。

Science. 1976 Apr 2;192(4234):62-4. doi: 10.1126/science.176726.

Pathology of the early lesion in multiple sclerosis.多发性硬化症早期病变的病理学

Hum Pathol. 1975 Sep;6(5):531-54. doi: 10.1016/s0046-8177(75)80040-2.

Theiler's virus infection in mice: an unusual biphasic disease process leading to demyelination.小鼠感染泰勒氏病毒：一种导致脱髓鞘的异常双相病程。

Infect Immun. 1975 May;11(5):1147-55. doi: 10.1128/iai.11.5.1147-1155.1975.

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