Arjomandy Bijan, Sahoo Narayan, Cox James, Lee Andrew, Gillin Michael
Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA.
Phys Med Biol. 2009 Jul 21;54(14):N295-302. doi: 10.1088/0031-9155/54/14/N02. Epub 2009 Jun 23.
Proton therapy for the treatment of cancer is delivered using either passively scattered or scanning beams. Each technique delivers a different amount of dose to the skin, because of the specific feature of their delivery system. The amount of dose delivered to the skin can play an important role in choosing the delivery technique for a specific site. To assess the differences in skin doses, we measured the surface doses associated with these two techniques. For the purpose of this investigation, the surface doses in a phantom were measured for ten prostate treatment fields planned with passively scattered proton beams and ten patients planned with spot scanning proton beams. The measured doses were compared to evaluate the differences in the amount of skin dose delivered by using these techniques. The results indicate that, on average, the patients treated with spot scanning proton beams received lower skin doses by an amount of 11.8% +/- 0.3% than did the patients treated with passively scattered proton beams. That difference could amount to 4 CGE per field for a prescribed dose of 76 CGE in 38 fractions treated with two equally weighted parallel opposed fields.
用于癌症治疗的质子治疗可通过被动散射束或扫描束来实现。由于其输送系统的特定特性,每种技术对皮肤的剂量输送量不同。输送到皮肤的剂量在为特定部位选择输送技术时可能起着重要作用。为了评估皮肤剂量的差异,我们测量了与这两种技术相关的表面剂量。为了本次研究,在体模中测量了用被动散射质子束计划的十个前列腺治疗野和用点扫描质子束计划治疗的十名患者的表面剂量。比较测量的剂量以评估使用这些技术输送的皮肤剂量量的差异。结果表明,平均而言,接受点扫描质子束治疗的患者所接受的皮肤剂量比接受被动散射质子束治疗的患者低11.8%±0.3%。对于用两个等权重的平行相对野治疗38次、处方剂量为76 CGE的情况,每个野的这种差异可能达到4 CGE。