贝克威思-威德曼综合征。
Beckwith-Wiedemann syndrome.
机构信息
Department of Genetics and Genome Biology, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario M5G 1X8, Canada.
出版信息
Eur J Hum Genet. 2010 Jan;18(1):8-14. doi: 10.1038/ejhg.2009.106.
Abstract
Beckwith-Wiedemann syndrome (BWS) is a model disorder for the study of imprinting, growth dysregulation, and tumorigenesis. Unique observations in this disorder point to an important embryonic developmental window relevant to the observations of increased monozygotic twinning and an increased rate of epigenetic errors after subfertility/assisted reproduction.
摘要
贝克威思-威德曼综合征（BWS）是研究印迹、生长失调和肿瘤发生的模型疾病。该疾病的独特观察结果指向一个重要的胚胎发育窗口，与增加的单卵双胞胎发生率和辅助生殖后的表观遗传错误率增加有关。
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Isolated fetal omphalocele, Beckwith-Wiedemann syndrome, and assisted reproductive technologies.孤立性胎儿脐膨出、贝克威思-维德曼综合征与辅助生殖技术。
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