Digestive Disorders Center, Tampa General Hospital, Tampa, FL, USA.
Surg Endosc. 2009 Dec;23(12):2644-9. doi: 10.1007/s00464-009-0508-1. Epub 2009 Jun 24.
Laparoscopic Heller myotomy was first undertaken in the early 1990s, and appreciable numbers of patients with 10-year follow-up periods are now available. This study was undertaken to determine long-term outcomes after laparoscopic Heller myotomy used to treat achalasia.
Of 337 patients who have undergone laparoscopic Heller myotomy since 1992, 47 who underwent myotomy more than 10 years ago have been followed through a prospectively maintained registry. Among many symptoms, patients scored dysphagia, chest pain, vomiting, regurgitation, choking, and heartburn before and after myotomy using a Likert scale with choices ranging from 0 (never/not bothersome) to 10 (always/very bothersome). Symptom scores before and after myotomy were compared using a Wilcoxon matched-pairs test. Data are reported as median (mean ± standard deviation).
The median length of the hospital stay was 2 days (mean, 3 ± 8.6 days; range, 1-60 days). Notable complications were infrequent after myotomy. There were no perioperative deaths. One patient required a redo myotomy after 5 years due to recurrence of symptoms. At this writing, 33 patients (70%) are still alive. The causes of death after discharge were unrelated to myotomy. The frequency and severity scores for dysphagia, chest pain, vomiting, regurgitation, choking, and heartburn all decreased significantly after laparoscopic Heller myotomy (p < 0.0001 for all).
Laparoscopic Heller myotomy can be undertaken with few complications. This procedure significantly decreases the frequency and severity of achalasia symptoms without promoting heartburn. The symptoms of achalasia are durably ameliorated by laparoscopic Heller myotomy during long-term follow-up evaluation, thereby promoting application of this procedure.
腹腔镜 Heller 肌切开术始于 20 世纪 90 年代初,现在已有大量接受了 10 年随访的患者。本研究旨在确定腹腔镜 Heller 肌切开术治疗贲门失弛缓症的长期疗效。
自 1992 年以来,共有 337 例患者接受了腹腔镜 Heller 肌切开术,其中 47 例患者在 10 年前接受了肌切开术,并通过前瞻性维护的登记处进行了随访。在许多症状中,患者在接受肌切开术前和术后使用 Likert 量表对吞咽困难、胸痛、呕吐、反流、窒息和烧心等症状进行评分,选项范围为 0(从不/不麻烦)至 10(总是/非常麻烦)。使用 Wilcoxon 配对检验比较肌切开术前和术后的症状评分。数据以中位数(平均值±标准差)表示。
中位住院时间为 2 天(平均值为 3±8.6 天;范围为 1-60 天)。肌切开术后并发症不常见。无围手术期死亡。1 例患者因症状复发在 5 年后需要再次肌切开术。截至目前,仍有 33 例(70%)患者存活。出院后的死因与肌切开术无关。腹腔镜 Heller 肌切开术后,吞咽困难、胸痛、呕吐、反流、窒息和烧心的频率和严重程度评分均显著降低(所有 P<0.0001)。
腹腔镜 Heller 肌切开术可在并发症较少的情况下进行。该手术显著降低了贲门失弛缓症症状的频率和严重程度,而不会促进烧心。在长期随访评估中,腹腔镜 Heller 肌切开术可持久改善贲门失弛缓症症状,从而促进该手术的应用。