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贲门失弛缓症肌切开术后对肌切开术前症状的回忆非常准确,这为症状改善的纵向研究提供了支持。

Postmyotomy recollection of premyotomy symptoms of achalasia is very accurate, supporting longitudinal studies of symptom improvement.

作者信息

Cowgill S M, Villalodid D, Al-Saadi S, Hedgecock J, Rosemurgy A S

机构信息

Digestive Disorders Center, Tampa General Hospital, and Department of Surgery, University of South Florida College of Medicine, P.O. Box 1289, Rm F145, Tampa, Florida 33601, USA.

出版信息

Surg Endosc. 2007 Dec;21(12):2183-6. doi: 10.1007/s00464-007-9332-7. Epub 2007 May 24.

Abstract

BACKGROUND

Recollection of preoperative symptom frequency and severity may change postoperatively, thus invalidating longitudinal studies. This study was undertaken to compare symptoms of achalasia before myotomy to patients' postoperative recollection of premyotomy symptoms.

METHODS

A total of 173 patients, 54% male, of median age 48 years, have undergone laparoscopic Heller myotomy and have been followed through a prospectively maintained registry. Preoperatively, patients scored the frequency and severity of their symptoms on a Likert scale: 0 (never/very bothersome) to 10 (always/very bothersome). Similarly, after laparoscopic Heller myotomy, patients scored the frequency and severity of their symptoms, and re-scored their preoperative symptoms. Data are presented as median, mean +/- SD.

RESULTS

Before myotomy, dysphagia, regurgitation, choking, chest pain, vomiting, and heartburn were particularly notable; symptom scores nearly globally improved after myotomy (p < 0.05 for all, Wilcoxon matched pairs test), especially obstructive symptoms. Postmyotomy recollection of premyotomy symptom frequency and severity was neither substantively nor consistently different from premyotomy scoring.

CONCLUSIONS

Before myotomy, patient symptom scores reflected the deleterious impact of achalasia. After myotomy, patient symptom scores dramatically improved, reflecting the favorable impact of laparoscopic Heller myotomy. Even years after myotomy, patient recollection of premyotomy symptom severity and frequency is very accurate and supports longitudinal studies of symptom improvement after myotomy.

摘要

背景

术前症状的频率和严重程度的回忆在术后可能会发生变化,从而使纵向研究无效。本研究旨在比较贲门失弛缓症患者在肌切开术前的症状与术后对肌切开术前症状的回忆。

方法

共有173例患者,其中54%为男性,中位年龄48岁,接受了腹腔镜Heller肌切开术,并通过前瞻性维护的登记系统进行随访。术前,患者根据李克特量表对症状的频率和严重程度进行评分:0(从不/非常困扰)至10(总是/非常困扰)。同样,在腹腔镜Heller肌切开术后,患者对症状的频率和严重程度进行评分,并对术前症状重新评分。数据以中位数、均值±标准差表示。

结果

在肌切开术前,吞咽困难、反流、呛咳、胸痛、呕吐和烧心尤为明显;肌切开术后症状评分几乎整体改善(所有p<0.05,Wilcoxon配对检验),尤其是梗阻性症状。肌切开术后对肌切开术前症状频率和严重程度的回忆与肌切开术前评分在本质上和一致性上均无差异。

结论

在肌切开术前,患者症状评分反映了贲门失弛缓症的有害影响。肌切开术后,患者症状评分显著改善,反映了腹腔镜Heller肌切开术的有利影响。即使在肌切开术后数年,患者对肌切开术前症状严重程度和频率的回忆也非常准确,并支持对肌切开术后症状改善的纵向研究。

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